Browsing Centre for Clinical Pharmacology by Author "Xiao, Q"
Now showing items 1-20 of 43
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Antiinflammatory actions of inorganic nitrate stabilize the atherosclerotic plaque
Khambata, RS; Ghosh, SM; Rathod, KS; Thevathasan, T; Filomena, F; Xiao, Q; Ahluwalia, A (2017-01-24) -
Atlas of Cell Repertoire Within Neointimal Lesions Is Metabolically Altered in Hypertensive Rats.
Sun, X; Wu, J; Zhang, X; Xie, C; Wei, H; Li, P; Yang, Y; Yuan, H; Cai, J; Xiao, Q (2024-01-19)BACKGROUND: High blood pressure has been suggested to accelerate vascular injury-induced neointimal formation and progression. However, little is known about the intricate relationships between vascular injury and hypertension ... -
The biological impact of blood pressure-associated genetic variants in the natriuretic peptide receptor C gene on human vascular smooth muscle
Ren, M; Ng, FL; Warren, HR; Witkowska, K; Baron, M; Jia, Z; Cabrera, C; Zhang, R; Mifsud, B; Munroe, PB (2018-01-01) -
Cardiolipin oxidized by ROS from complex II acts as a target of gasdermin D to drive mitochondrial pore and heart dysfunction in endotoxemia.
Tang, Y; Wu, J; Sun, X; Tan, S; Li, W; Yin, S; Liu, L; Chen, Y; Liu, Y; Tan, Q (Cell Press, 2024-05-15)Cardiac dysfunction, an early complication of endotoxemia, is the major cause of death in intensive care units. No specific therapy is available at present for this cardiac dysfunction. Here, we show that the N-terminal ... -
Causal Role for Neutrophil Elastase in Thoracic Aortic Dissection in Mice
Yang, M; Zhou, X; Pearce, SWA; Yang, Z; Chen, Q; Niu, K; Liu, C; Luo, J; Li, D; Shao, Y (2023) -
Cbx3 inhibits vascular smooth muscle cell proliferation, migration, and neointima formation
Zhang, C; Chen, D; Maguire, EM; He, S; Chen, J; An, W; Yang, M; Afzal, TA; Luong, LA; Zhang, L (2018-03) -
Cezanne is a critical regulator of pathological arterial remodelling by targeting β-catenin signalling.
An, W; Luong, LA; Bowden, NP; Yang, M; Wu, W; Zhou, X; Liu, C; Niu, K; Luo, J; Zhang, C (Oxford University Press, 2021-02-18)AIM: Pathological arterial remodelling including neointimal hyperplasia and atherosclerosis is the main underlying cause for occluding arterial diseases. Cezanne is a novel deubiquitinating enzyme, functioning as a NF-кB ... -
Coronary-Heart-Disease-Associated Genetic Variant at the COL4A1/COL4A2 Locus Affects COL4A1/COL4A2 Expression, Vascular Cell Survival, Atherosclerotic Plaque Stability and Risk of Myocardial Infarction
Yang, W; Ng, FL; Chan, K; Pu, X; Poston, RN; Ren, M; An, W; Zhang, R; Wu, J; Yan, S (2016-07) -
Differentiation and Application of Induced Pluripotent Stem Cell-Derived Vascular Smooth Muscle Cells
Maguire, EM; Xiao, Q; Xu, Q (2017) -
The Effect of Lymphangiogenesis in Transplant Arteriosclerosis
Chen, K; Mou, R; Zhu, P; Xu, X; Wang, H; Jiang, L; Hu, Y; Hu, X; Ma, L; Xiao, Q (2023) -
Electron Transfer Flavoprotein (ETF) alpha Controls Blood Vessel Development by Regulating Endothelial Mitochondrial Bioenergetics and Oxygen Consumption
Yan, Y; Xu, Y; Yang, X; Li, Z; Niu, K; Liu, C; Zhao, M; Xiao, Q; Wu, W (2022) -
The FES Gene at the 15q26 Coronary-Artery-Disease Locus Inhibits Atherosclerosis
Karamanavi, E; McVey, DG; van der Laan, SW; Stanczyk, PJ; Morris, GE; Wang, Y; Yang, W; Chan, K; Poston, RN; Luo, J (2022) -
Foam cell formation: A new target for fighting atherosclerosis and cardiovascular disease.
Maguire, EM; Pearce, SWA; Xiao, Q (2019-01)During atherosclerosis, the gradual accumulation of lipids into the subendothelial space of damaged arteries results in several lipid modification processes followed by macrophage uptake in the arterial wall. The way in ... -
FUNCTIONAL ROLE OF MICRORNA-214 IN MODULATING VASCULAR SMOOTH MUSCLE CELL FUNCTIONS AND NEOINTIMA FORMATION
Afzal, TA; Xiao, Q (2016-06) -
Genetic and Pharmacologic Inhibition of the Neutrophil Elastase Inhibits Experimental Atherosclerosis
Wen, G; An, W; Chen, J; Maguire, EM; Chen, Q; Yang, F; Pearce, SWA; Kyriakides, M; Zhang, L; Ye, S (2018-02-20) -
HNRNPA1 IS A CRITICAL REGULATOR IN VASCULAR SMOOTH MUSCLE CELL FUNCTIONS AND NEOINTIMA HYPERPLASIA
Weiwei, AN; Xiao, Q (2016-06) -
Impact of Local Alloimmunity and Recipient Cells in Transplant Arteriosclerosis
Cai, J; Deng, J; Gu, W; Ni, Z; Liu, Y; Kamra, Y; Saxena, A; Hu, Y; Yuan, H; Xiao, Q (2020-09-25) -
Induction of Heme Oxygenase-1 Modifies the Systemic Immunity and Reduces Atherosclerotic Lesion Development in ApoE Deficient Mice
Yao, L; Hao, Y; Wen, G; Xiao, Q; Wu, P; Wang, J; Liu, J (2022) -
Matrix Metalloproteinase in Abdominal Aortic Aneurysm and Aortic Dissection
Maguire, EM; Pearce, SWA; Xiao, R; Oo, AY; Xiao, Q (2019) -
Meta-Analysis of Single-Cell RNA-Seq Data Reveals the Mechanism of Formation and Heterogeneity of Tertiary Lymphoid Organ in Vascular Disease
Sun, X; Lu, Y; Wu, J; Wen, Q; Li, Z; Tang, Y; Shi, Y; He, T; Liu, L; Huang, W (2023)