Browsing Centre for Clinical Pharmacology by Author "Wong, TY"
Now showing items 1-12 of 12
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Gene-educational attainment interactions in a multi-ancestry genome-wide meta-analysis identify novel blood pressure loci.
de Las Fuentes, L; Sung, YJ; Noordam, R; Winkler, T; Feitosa, MF; Schwander, K; Bentley, AR; Brown, MR; Guo, X; Manning, A (Springer Nature, 2020-05-05)Educational attainment is widely used as a surrogate for socioeconomic status (SES). Low SES is a risk factor for hypertension and high blood pressure (BP). To identify novel BP loci, we performed multi-ancestry meta-analyses ... -
Gene-educational attainment interactions in a multi-population genome-wide meta-analysis identify novel lipid loci
de las Fuentes, L; Schwander, KL; Brown, MR; Bentley, AR; Winkler, TW; Sung, YJ; Munroe, PB; Miller, CL; Aschard, H; Aslibekyan, S -
The genetic architecture of type 2 diabetes
Fuchsberger, C; Flannick, J; Teslovich, TM; Mahajan, A; Agarwala, V; Gaulton, KJ; Ma, C; Fontanillas, P; Moutsianas, L; McCarthy, DJ (2016-08-04) -
Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk
Ehret, GB; Munroe, PB; Rice, KM; Bochud, M; Johnson, AD; Chasman, DI; Smith, AV; Tobin, MD; Verwoert, GC; Hwang, SJ (2011-10-06) -
A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure
Sung, YJ; Winkler, TW; de las Fuentes, L; Bentley, AR; Brown, MR; Kraja, AT; Schwander, K; Ntalla, I; Guo, X; Franceschini, N (2018-03-01) -
Multi-Ancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions.
de Vries, PS; Brown, MR; Bentley, AR; Sung, YJ; Winkler, TW; Ntalla, I; Schwander, K; Kraja, AT; Guo, X; Franceschini, N (Oxford University Press, 2019-01-29)An individual's lipid profile is influenced by genetic variants and alcohol consumption, but the contribution of interactions between these exposures has not been studied. We therefore incorporated gene-alcohol interactions ... -
Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids
Bentley, AR; Sung, YJ; Brown, MR; Winkler, TW; Kraja, AT; Ntalla, I; Schwander, K; Chasman, DI; Lim, E; Deng, X (Nature Research (part of Springer Nature), 2019-03-29)The concentrations of high- and low-density-lipoprotein cholesterol and triglycerides are influenced by smoking, but it is unknown whether genetic associations with lipids may be modified by smoking. We conducted a ... -
A multi-ancestry genome-wide study incorporating gene-smoking interactions identifies multiple new loci for pulse pressure and mean arterial pressure
Sung, YJ; de Las Fuentes, L; Winkler, TW; Chasman, DI; Bentley, AR; Kraja, AT; Ntalla, I; Warren, HR; Guo, X; Schwander, K (2019-08-01) -
Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries
Feitosa, MF; Kraja, AT; Chasman, DI; Sung, YJ; Winkler, TW; Ntalla, I; Guo, X; Franceschini, N; Cheng, C-Y; Sim, X (2018-06-18) -
Novel genetic loci associated with hippocampal volume
Hibar, DP; Adams, HHH; Jahanshad, N; Chauhan, G; Stein, JL; Hofer, E; Renteria, ME; Bis, JC; Arias-Vasquez, A; Ikram, MK (2017-01-18) -
Seven new loci associated with age-related macular degeneration
Fritsche, LG; Chen, W; Schu, M; Yaspan, BL; Yu, Y; Thorleifsson, G; Zack, DJ; Arakawa, S; Cipriani, V; Ripke, S (2013-03-03) -
Tissue-Specific Alteration of Metabolic Pathways Influences Glycemic Regulation
Ng, N; Willems, SM; Fernandez, J; Fine, RS; Wheeler, E; Wessel, J; Kitajima, H; Marenne, G; Rundle, JK; Sim, X (2019-10-15)