Browsing Centre for Clinical Pharmacology by Author "Wilson, JG"
Now showing items 1-20 of 24
-
Common and Rare Coding Genetic Variation Underlying the Electrocardiographic PR Interval
Lin, H; van Setten, J; Smith, AV; Bihlmeyer, NA; Warren, HR; Brody, JA; Radmanesh, F; Hall, L; Grarup, N; Mueller-Nurasyid, M (2018-05) -
Concept, Design and Implementation of a Cardiovascular Gene-Centric 50 K SNP Array for Large-Scale Genomic Association Studies
Keating, BJ; Tischfield, S; Murray, SS; Bhangale, T; Price, TS; Glessner, JT; Galver, L; Barrett, JC; Grant, SFA; Farlow, DN (2008-10-31) -
Directional dominance on stature and cognition in diverse human populations
Joshi, PK; Esko, T; Mattsson, H; Eklund, N; Gandin, I; Nutile, T; Jackson, AU; Schurmann, C; Smith, AV; Zhang, W (2015-07-23) -
Discovery and fine-mapping of height loci via high-density imputation of GWASs in individuals of African ancestry
Graff, M; Justice, AE; Young, KL; Marouli, E; Zhang, X; Fine, RS; Lim, E; Buchanan, V; Rand, K; Feitosa, MF (2021) -
Effects of Calcium, Magnesium, and Potassium Concentrations on Ventricular Repolarization in Unselected Individuals
Noordam, R; Young, WJ; Salman, R; Kanters, JK; van den Berg, ME; van Heemst, D; Lin, HJ; Barreto, SM; Biggs, ML; Biino, G (2019-06-25) -
Exome-chip meta-analysis identifies novel loci associated with cardiac conduction, including ADAMTS6
Prins, BP; Mead, TJ; Brody, JA; Sveinbjornsson, G; Ntalla, I; Bihlmeyer, NA; van den Berg, M; Bork-Jensen, J; Cappellani, S; Van Duijvenboden, S (2018-07-17) -
Exome-wide association study of plasma lipids in > 300,000 individuals
Liu, DJ; Peloso, GM; Yu, H; Butterworth, AS; Wang, X; Mahajan, A; Saleheen, D; Emdin, C; Alam, D; Alves, AC (2017-12) -
ExomeChip-Wide Analysis of 95 626 Individuals Identifies 10 Novel Loci Associated With QT and JT Intervals
Bihlmeyer, NA; Brody, JA; Smith, AV; Warren, HR; Lin, H; Isaacs, A; Liu, C-T; Marten, J; Radmanesh, F; Hall, LM (2018-01) -
Genetic analyses of the electrocardiographic QT interval and its components identify additional loci and pathways
Young, WJ; Lahrouchi, N; Isaacs, A; Duong, TV; Foco, L; Ahmed, F; Brody, JA; Salman, R; Noordam, R; Benjamins, J-W (2022) -
Genetic architecture of spatial electrical biomarkers for cardiac arrhythmia and relationship with cardiovascular disease.
Young, WJ; Haessler, J; Benjamins, J-W; Repetto, L; Yao, J; Isaacs, A; Harper, AR; Ramirez, J; Garnier, S; van Duijvenboden, S (2023-03-14)The 3-dimensional spatial and 2-dimensional frontal QRS-T angles are measures derived from the vectorcardiogram. They are independent risk predictors for arrhythmia, but the underlying biology is unknown. Using multi-ancestry ... -
The genetic architecture of type 2 diabetes
Fuchsberger, C; Flannick, J; Teslovich, TM; Mahajan, A; Agarwala, V; Gaulton, KJ; Ma, C; Fontanillas, P; Moutsianas, L; McCarthy, DJ (2016-08-04) -
Genome-wide association meta-analysis of 30,000 samples identifies seven novel loci for quantitative ECG traits.
van Setten, J; Verweij, N; Mbarek, H; Niemeijer, MN; Trompet, S; Arking, DE; Brody, JA; Gandin, I; Grarup, N; Hall, LM (Nature Publishing Group, 2019-01-24)Genome-wide association studies (GWAS) of quantitative electrocardiographic (ECG) traits in large consortia have identified more than 130 loci associated with QT interval, QRS duration, PR interval, and heart rate (RR ... -
A genome-wide interaction analysis of tricyclic/tetracyclic antidepressants and RR and QT intervals: a pharmacogenomics study from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium
Noordam, R; Sitlani, CM; Avery, CL; Stewart, JD; Gogarten, SM; Wiggins, KL; Trompet, S; Warren, HR; Sun, F; Evans, DS (2017-05) -
Implicating genes, pleiotropy, and sexual dimorphism at blood lipid loci through multi-ancestry meta-analysis
Kanoni, S; Graham, SE; Wang, Y; Surakka, I; Ramdas, S; Zhu, X; Clarke, SL; Bhatti, KF; Vedantam, S; Winkler, TW (2022) -
A multi-layer functional genomic analysis to understand noncoding genetic variation in lipids
Ramdas, S; Judd, J; Graham, SE; Kanoni, S; Wang, Y; Surakka, I; Wenz, B; Clarke, SL; Chesi, A; Wells, A (2022) -
New Blood Pressure-Associated Loci Identified in Meta-Analyses of 475000 Individuals
Kraja, AT; Cook, JP; Warren, HR; Surendran, P; Liu, C; Evangelou, E; Manning, AK; Grarup, N; Drenos, F; Sim, X (American Heart Association, 2017-10-13)Background— Genome-wide association studies have recently identified >400 loci that harbor DNA sequence variants that influence blood pressure (BP). Our earlier studies identified and validated 56 single nucleotide variants ... -
Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity
Turcot, V; Lu, Y; Highland, HM; Schurmann, C; Justice, AE; Fine, RS; Bradfield, JP; Esko, T; Giri, A; Graff, M (2018-01) -
Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity (vol 50, pg 26, 2017)
Turcot, V; Lu, Y; Highland, HM; Schurmann, C; Justice, AE; Fine, RS; Bradfield, JP; Esko, T; Giri, A; Graff, M (2019-07) -
Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity (vol 50, pg 26, 2018)
Turcot, V; Lu, Y; Highland, HM; Schurmann, C; Justice, AE; Fine, RS; Bradfield, JP; Esko, T; Giri, A; Graff, M (2018-05) -
Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity (vol 50, pg 765, 2017)
Turcot, V; Lu, Y; Highland, HM; Schurmann, C; Justice, AE; Fine, RS; Bradfield, JP; Esko, T; Giri, A; Graff, M (2018-05)