Browsing Centre for Clinical Pharmacology by Author "Raffel, LJ"
Now showing items 1-6 of 6
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Gene-educational attainment interactions in a multi-ancestry genome-wide meta-analysis identify novel blood pressure loci.
de Las Fuentes, L; Sung, YJ; Noordam, R; Winkler, T; Feitosa, MF; Schwander, K; Bentley, AR; Brown, MR; Guo, X; Manning, A (Springer Nature, 2020-05-05)Educational attainment is widely used as a surrogate for socioeconomic status (SES). Low SES is a risk factor for hypertension and high blood pressure (BP). To identify novel BP loci, we performed multi-ancestry meta-analyses ... -
Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk
Ehret, GB; Munroe, PB; Rice, KM; Bochud, M; Johnson, AD; Chasman, DI; Smith, AV; Tobin, MD; Verwoert, GC; Hwang, SJ (2011-10-06) -
Genome-wide analysis identifies 12 loci influencing human reproductive behavior
Barban, N; Jansen, R; de Vlaming, R; Vaez, A; Mandemakers, JJ; Tropf, FC; Shen, X; Wilson, JF; Chasman, DI; Nolte, IM (2016-12) -
Multi-Ancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions.
de Vries, PS; Brown, MR; Bentley, AR; Sung, YJ; Winkler, TW; Ntalla, I; Schwander, K; Kraja, AT; Guo, X; Franceschini, N (Oxford University Press, 2019-01-29)An individual's lipid profile is influenced by genetic variants and alcohol consumption, but the contribution of interactions between these exposures has not been studied. We therefore incorporated gene-alcohol interactions ... -
Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries
Feitosa, MF; Kraja, AT; Chasman, DI; Sung, YJ; Winkler, TW; Ntalla, I; Guo, X; Franceschini, N; Cheng, C-Y; Sim, X (2018-06-18) -
The trans-ancestral genomic architecture of glycemic traits.
Chen, J; Spracklen, CN; Marenne, G; Varshney, A; Corbin, LJ; Luan, J; Willems, SM; Wu, Y; Zhang, X; Horikoshi, M (2021-05-31)Glycemic traits are used to diagnose and monitor type 2 diabetes and cardiometabolic health. To date, most genetic studies of glycemic traits have focused on individuals of European ancestry. Here we aggregated genome-wide ...