Browsing Centre for Clinical Pharmacology by Author "R'Bibo, L"
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Mitochondria function associated genes contribute to Parkinson's Disease risk and later age at onset
Billingsley, KJ; Barbosa, IA; Bandres-Ciga, S; Quinn, JP; Bubb, VJ; Deshpande, C; Botia, JA; Reynolds, RH; Zhang, D; Simpson, MA (Springer Nature, 2019-05-22)Mitochondrial dysfunction has been implicated in the etiology of monogenic Parkinson’s disease (PD). Yet the role that mitochondrial processes play in the most common form of the disease; sporadic PD, is yet to be fully ... -
Moving beyond neurons: the role of cell type-specific gene regulation in Parkinson's disease heritability
Reynolds, RH; Botia, J; Nalls, MA; Hardy, J; Taliun, SAG; Ryten, M; Noyce, AJ; Nicolas, A; Cookson, MR; Bandres-Ciga, S (Springer Nature, 2019-04-17)Parkinson’s disease (PD), with its characteristic loss of nigrostriatal dopaminergic neurons and deposition of α-synuclein in neurons, is often considered a neuronal disorder. However, in recent years substantial evidence ...