Browsing Centre for Clinical Pharmacology by Author "Qi, L"
Now showing items 1-16 of 16
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Association of Birth Weight With Type 2 Diabetes and Glycemic Traits A Mendelian Randomization Study
Huang, T; Wang, T; Zheng, Y; Ellervik, C; Li, X; Gao, M; Fang, Z; Chai, J-F; Ahluwalia, TVS; Wang, Y (2019-09)Importance: Observational studies have shown associations of birth weight with type 2 diabetes (T2D) and glycemic traits, but it remains unclear whether these associations represent causal associations. Objective: To ... -
Defining the role of common variation in the genomic and biological architecture of adult human height
Wood, AR; Esko, T; Yang, J; Vedantam, S; Pers, TH; Gustafsson, S; Chun, AY; Estrada, K; Luan, J; Kutalik, Z (2014-11) -
Discovery of novel heart rate-associated loci using the Exome Chip
van den Berg, ME; Warren, HR; Cabrera, CP; Verweij, N; Mifsud, B; Haessler, J; Bihlmeyer, NA; Fu, Y-P; Weiss, S; Lin, HJ (2017-06-15) -
The genetic architecture of type 2 diabetes
Fuchsberger, C; Flannick, J; Teslovich, TM; Mahajan, A; Agarwala, V; Gaulton, KJ; Ma, C; Fontanillas, P; Moutsianas, L; McCarthy, DJ (2016-08-04) -
Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci
Gaulton, KJ; Ferreira, T; Lee, Y; Raimondo, A; Maegi, R; Reschen, ME; Mahajan, A; Locke, A; Rayner, NW; Robertson, N (2015-12) -
Genetic insights into resting heart rate and its role in cardiovascular disease
van de Vegte, Y; Eppinga, RP; van der Ende, MY; Hagemeijer, Y; Mahendran, YV; Salfati, EY; Smith, AE; Tan, V; Arking, DV; Ntalla, I (2023) -
Genetic Predisposition to Coronary Artery Disease in Type 2 Diabetes Mellitus
van Zuydam, NR; Ladenvall, C; Voight, BF; Strawbridge, RJ; Fernandez-Tajes, J; Rayner, NW; Robertson, NR; Mahajan, A; Vlachopoulou, E; Goel, A (Wolters Kluwer Health, Inc. on behalf of the American Heart Association,, 2020-08-13) -
Genetic studies of body mass index yield new insights for obesity biology
Locke, AE; Kahali, B; Berndt, SI; Justice, AE; Pers, TH; Day, FR; Powell, C; Vedantam, S; Buchkovich, ML; Yang, J (2015-02-12) -
Genome-Wide Association Scan Meta-Analysis Identifies Three Loci Influencing Adiposity and Fat Distribution
Lindgren, CM; Heid, IM; Randall, JC; Lamina, C; Steinthorsdottir, V; Qi, L; Speliotes, EK; Thorleifsson, G; Willer, CJ; Herrera, BM (2009-06) -
Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits
Justice, AE; Winkler, TW; Feitosa, MF; Graff, M; Fisher, VA; Young, K; Barata, L; Deng, X; Czajkowski, J; Hadley, D (2017-04-26) -
The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study (vol 11, e1005378, 2015)
Winkler, TW; Justice, AE; Graff, M; Barata, L; Feitosa, MF; Chu, S; Czajkowski, J; Esko, T; Fall, T; Kilpelainen, TO (2016-06) -
New genetic loci link adipose and insulin biology to body fat distribution
Shungin, D; Winkler, TW; Croteau-Chonka, DC; Ferreira, T; Lockes, AE; Maegi, R; Strawbridge, RJ; Pers, TH; Fischer, K; Justice, AE (2015-02-12) -
A principal component meta-analysis on multiple anthropometric traits identifies novel loci for body shape
Ried, JS; Jeff, JM; Chu, AY; Bragg-Gresham, JL; van Dongen, J; Huffman, JE; Ahluwalia, TS; Cadby, G; Eklund, N; Eriksson, J (2016-11-23) -
Sex-stratified Genome-wide Association Studies Including 270,000 Individuals Show Sexual Dimorphism in Genetic Loci for Anthropometric Traits
Randall, JC; Winkler, TW; Kutalik, Z; Berndt, SI; Jackson, AU; Monda, KL; Kilpelaeinen, TO; Esko, T; Maegi, R; Li, S (2013-06) -
SOS2 and ACP1 Loci Identified through Large-Scale Exome Chip Analysis Regulate Kidney Development and Function.
Li, M; Li, Y; Weeks, O; Mijatovic, V; Teumer, A; Huffman, JE; Tromp, G; Fuchsberger, C; Gorski, M; Lyytikäinen, L-P (2017-03)Genome-wide association studies have identified >50 common variants associated with kidney function, but these variants do not fully explain the variation in eGFR. We performed a two-stage meta-analysis of associations ... -
The trans-ancestral genomic architecture of glycemic traits.
Chen, J; Spracklen, CN; Marenne, G; Varshney, A; Corbin, LJ; Luan, J; Willems, SM; Wu, Y; Zhang, X; Horikoshi, M (2021-05-31)Glycemic traits are used to diagnose and monitor type 2 diabetes and cardiometabolic health. To date, most genetic studies of glycemic traits have focused on individuals of European ancestry. Here we aggregated genome-wide ...