Browsing Centre for Clinical Pharmacology by Author "Laakso, M"
Now showing items 1-20 of 46
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Defining the role of common variation in the genomic and biological architecture of adult human height
Wood, AR; Esko, T; Yang, J; Vedantam, S; Pers, TH; Gustafsson, S; Chun, AY; Estrada, K; Luan, J; Kutalik, Z (2014-11) -
Directional dominance on stature and cognition in diverse human populations
Joshi, PK; Esko, T; Mattsson, H; Eklund, N; Gandin, I; Nutile, T; Jackson, AU; Schurmann, C; Smith, AV; Zhang, W (2015-07-23) -
Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals
Surendran, P; Feofanova, EV; Lahrouchi, N; Ntalla, I; Karthikeyan, S; Cook, J; Chen, L; Mifsud, B; Yao, C; Kraja, AT (2020) -
Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals (vol 52, pg 1314, 2020)
Surendran, P; Feofanova, EV; Lahrouchi, N; Ntalla, I; Karthikeyan, S; Cook, J; Chen, L; Mifsud, B; Yao, C; Kraja, AT (2021) -
Exome Chip Meta-analysis Fine Maps Causal Variants and Elucidates the Genetic Architecture of Rare Coding Variants in Smoking and Alcohol Use
Brazel, DM; Jiang, Y; Hughey, JM; Turcot, V; Zhan, X; Gong, J; Batini, C; Weissenkampen, JD; Liu, M; Barnes, DR (2019-06-01) -
Exome-wide association study of plasma lipids in > 300,000 individuals
Liu, DJ; Peloso, GM; Yu, H; Butterworth, AS; Wang, X; Mahajan, A; Saleheen, D; Emdin, C; Alam, D; Alves, AC (2017-12) -
Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits
Evangelou, E; Warren, HR; Mosen-Ansorena, D; Mifsu, B; Pazoki, R; Gao, H; Ntritsos, G; Dimou, N; Cabrer, CP; Karaman, I (2018-10) -
The genetic architecture of type 2 diabetes
Fuchsberger, C; Flannick, J; Teslovich, TM; Mahajan, A; Agarwala, V; Gaulton, KJ; Ma, C; Fontanillas, P; Moutsianas, L; McCarthy, DJ (2016-08-04) -
Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci
Gaulton, KJ; Ferreira, T; Lee, Y; Raimondo, A; Maegi, R; Reschen, ME; Mahajan, A; Locke, A; Rayner, NW; Robertson, N (2015-12) -
Genetic Predisposition to Coronary Artery Disease in Type 2 Diabetes Mellitus
van Zuydam, NR; Ladenvall, C; Voight, BF; Strawbridge, RJ; Fernandez-Tajes, J; Rayner, NW; Robertson, NR; Mahajan, A; Vlachopoulou, E; Goel, A (Wolters Kluwer Health, Inc. on behalf of the American Heart Association,, 2020-08-13) -
Genetic studies of body mass index yield new insights for obesity biology
Locke, AE; Kahali, B; Berndt, SI; Justice, AE; Pers, TH; Day, FR; Powell, C; Vedantam, S; Buchkovich, ML; Yang, J (2015-02-12) -
Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk
Ehret, GB; Munroe, PB; Rice, KM; Bochud, M; Johnson, AD; Chasman, DI; Smith, AV; Tobin, MD; Verwoert, GC; Hwang, SJ (2011-10-06) -
Genome-Wide Association Scan Meta-Analysis Identifies Three Loci Influencing Adiposity and Fat Distribution
Lindgren, CM; Heid, IM; Randall, JC; Lamina, C; Steinthorsdottir, V; Qi, L; Speliotes, EK; Thorleifsson, G; Willer, CJ; Herrera, BM (2009-06) -
Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits
Justice, AE; Winkler, TW; Feitosa, MF; Graff, M; Fisher, VA; Young, K; Barata, L; Deng, X; Czajkowski, J; Hadley, D (2017-04-26) -
A genomic approach to therapeutic target validation identifies a glucose-lowering GLP1R variant protective for coronary heart disease
Scott, RA; Freitag, DF; Li, L; Chu, AY; Surendran, P; Young, R; Grarup, N; Stancakova, A; Chen, Y; Varga, TV (2016-06-01) -
Genomic correlates of glatiramer acetate adverse cardiovascular effects lead to a novel locus mediating coronary risk.
Brænne, I; Zeng, L; Willenborg, C; Tragante, V; Kessler, T; CARDIoGRAM Consortium; CARDIoGRAMplusC4D Consortium; Willer, CJ; Laakso, M; Wallentin, L (2017)Glatiramer acetate is used therapeutically in multiple sclerosis but also known for adverse effects including elevated coronary artery disease (CAD) risk. The mechanisms underlying the cardiovascular side effects of the ... -
Implicating genes, pleiotropy, and sexual dimorphism at blood lipid loci through multi-ancestry meta-analysis
Kanoni, S; Graham, SE; Wang, Y; Surakka, I; Ramdas, S; Zhu, X; Clarke, SL; Bhatti, KF; Vedantam, S; Winkler, TW (2022) -
The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study (vol 11, e1005378, 2015)
Winkler, TW; Justice, AE; Graff, M; Barata, L; Feitosa, MF; Chu, S; Czajkowski, J; Esko, T; Fall, T; Kilpelainen, TO (2016-06) -
A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure
Sung, YJ; Winkler, TW; de las Fuentes, L; Bentley, AR; Brown, MR; Kraja, AT; Schwander, K; Ntalla, I; Guo, X; Franceschini, N (2018-03-01) -
Meta-analysis of up to 622,409 individuals identifies 40 novel smoking behaviour associated genetic loci.
Erzurumluoglu, AM; Liu, M; Jackson, VE; Barnes, DR; Datta, G; Melbourne, CA; Young, R; Batini, C; Surendran, P; Jiang, T (Springer Nature, 2019-01-07)Smoking is a major heritable and modifiable risk factor for many diseases, including cancer, common respiratory disorders and cardiovascular diseases. Fourteen genetic loci have previously been associated with smoking ...