Browsing Centre for Clinical Pharmacology by Author "Jackson, RD"
Now showing items 1-9 of 9
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Genetic analyses of the electrocardiographic QT interval and its components identify additional loci and pathways
Young, WJ; Lahrouchi, N; Isaacs, A; Duong, TV; Foco, L; Ahmed, F; Brody, JA; Salman, R; Noordam, R; Benjamins, J-W (2022) -
Genetic architecture of spatial electrical biomarkers for cardiac arrhythmia and relationship with cardiovascular disease.
Young, WJ; Haessler, J; Benjamins, J-W; Repetto, L; Yao, J; Isaacs, A; Harper, AR; Ramirez, J; Garnier, S; van Duijvenboden, S (2023-03-14)The 3-dimensional spatial and 2-dimensional frontal QRS-T angles are measures derived from the vectorcardiogram. They are independent risk predictors for arrhythmia, but the underlying biology is unknown. Using multi-ancestry ... -
Implicating genes, pleiotropy, and sexual dimorphism at blood lipid loci through multi-ancestry meta-analysis
Kanoni, S; Graham, SE; Wang, Y; Surakka, I; Ramdas, S; Zhu, X; Clarke, SL; Bhatti, KF; Vedantam, S; Winkler, TW (2022) -
Multi-ancestry GWAS of the electrocardiographic PR interval identifies 202 loci underlying cardiac conduction
Ntalla, I; Weng, L-C; Cartwright, JH; Hall, AW; Sveinbjornsson, G; Tucker, NR; Choi, SH; Chaffin, MD; Roselli, C; Barnes, MR (2020-05-21) -
A multi-layer functional genomic analysis to understand noncoding genetic variation in lipids
Ramdas, S; Judd, J; Graham, SE; Kanoni, S; Wang, Y; Surakka, I; Wenz, B; Clarke, SL; Chesi, A; Wells, A (2022) -
A saturated map of common genetic variants associated with human height
Yengo, L; Vedantam, S; Marouli, E; Sidorenko, J; Bartell, E; Sakaue, S; Graff, M; Eliasen, AU; Jiang, Y; Raghavan, S (2022) -
SOS2 and ACP1 Loci Identified through Large-Scale Exome Chip Analysis Regulate Kidney Development and Function.
Li, M; Li, Y; Weeks, O; Mijatovic, V; Teumer, A; Huffman, JE; Tromp, G; Fuchsberger, C; Gorski, M; Lyytikäinen, L-P (2017-03)Genome-wide association studies have identified >50 common variants associated with kidney function, but these variants do not fully explain the variation in eGFR. We performed a two-stage meta-analysis of associations ... -
Systematic Evaluation of Pleiotropy Identifies 6 Further Loci Associated With Coronary Artery Disease
Webb, TR; Erdmann, J; Stirrups, KE; Stitziel, NO; Masca, NGD; Jansen, H; Kanoni, S; Nelson, CP; Ferrario, PG; Koenig, IR (2017-02-21) -
Testing the role of predicted gene knockouts in human anthropometric trait variation
Lessard, S; Manning, AK; Low-Kam, C; Auer, PL; Giri, A; Graff, M; Schurmann, C; Yaghootkar, H; Luan, J; Esko, T (2016-05-15)