Browsing Centre for Clinical Pharmacology by Author "Da Dalt, L"
Now showing items 1-1 of 1
-
Myeloid apolipoprotein E controls dendritic cell antigen presentation and T cell activation.
Bonacina, F; Coe, D; Wang, G; Longhi, MP; Baragetti, A; Moregola, A; Garlaschelli, K; Uboldi, P; Pellegatta, F; Grigore, L (2018-08-06)Cholesterol homeostasis has a pivotal function in regulating immune cells. Here we show that apolipoprotein E (apoE) deficiency leads to the accumulation of cholesterol in the cell membrane of dendritic cells (DC), resulting ...