Browsing Centre for Clinical Pharmacology by Author "Cabrera, CP"
Now showing items 1-20 of 28
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199Genetic architecture of left ventricular phenotypes derived from 17,000 CMR studies in the UK Biobank population imaging cohort
Aung, N; Vargas, JD; Manichaikul, AW; Yang, C; Cabrera, CP; Warren, HR; Fung, K; Tzanis, E; Barnes, MR; Bluemke, DA (2019-06-01) -
An Academic Clinician's Road Map to Hypertension Genomics: Recent Advances and Future Directions MMXX.
Magavern, EF; Warren, HR; Ng, FL; Cabrera, CP; Munroe, PB; Caulfield, MJ (2021-01-04)At the dawn of the new decade, it is judicious to reflect on the boom of knowledge about polygenic risk for essential hypertension supplied by the wealth of genome-wide association studies. Hypertension continues to account ... -
Aldosterone-producing adenomas with dual mutations of GNA11/Q and CTNNB1 lead to hypertension in puberty, pregnancy or menopause, and complete cure by adrenalectomy
Argentesi, G; Zhou, J; Azizan, E; Cabrera, CP; Cottrell, E; Wu, X; Goodchild, E; Foo, R; Mein, C; Wozniak, E (2021) -
Correction: Signatures of inflammation and impending multiple organ dysfunction in the hyperacute phase of trauma: A prospective cohort study.
Cabrera, CP; Manson, J; Shepherd, JM; Torrance, HD; Watson, D; Longhi, MP; Hoti, M; Patel, MB; O'Dwyer, M; Nourshargh, S (Public Library of Science, 2018-10-31)[This corrects the article DOI: 10.1371/journal.pmed.1002352.]. -
Corrigendum: Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.
Warren, HR; Evangelou, E; Cabrera, CP; Gao, H; Ren, M; Mifsud, B; Ntalla, I; Surendran, P; Liu, C; Cook, JP (2017-09-27) -
Differentially expressed genes for atrial fibrillation identified by RNA sequencing from paired human left and right atrial appendages
Thomas, AM; Cabrera, CP; Finlay, M; Lall, K; Nobles, M; Schilling, RJ; Wood, K; Mein, CA; Barnes, MR; Munroe, PB (2019-08) -
Discovery of novel heart rate-associated loci using the Exome Chip
van den Berg, ME; Warren, HR; Cabrera, CP; Verweij, N; Mifsud, B; Haessler, J; Bihlmeyer, NA; Fu, Y-P; Weiss, S; Lin, HJ (2017-06-15) -
Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals
Surendran, P; Feofanova, EV; Lahrouchi, N; Ntalla, I; Karthikeyan, S; Cook, J; Chen, L; Mifsud, B; Yao, C; Kraja, AT (2020) -
Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals (vol 52, pg 1314, 2020)
Surendran, P; Feofanova, EV; Lahrouchi, N; Ntalla, I; Karthikeyan, S; Cook, J; Chen, L; Mifsud, B; Yao, C; Kraja, AT (2021) -
EAP1 regulation of GnRH promoter activity is important for human pubertal timing.
Mancini, A; Howard, SR; Cabrera, CP; Barnes, MR; David, A; Wehkalampi, K; Heger, S; Lomniczi, A; Guasti, L; Ojeda, SR (Oxford University Press, 2019-01-04)The initiation of puberty is orchestrated by an augmentation of gonadotropin-releasing hormone (GnRH) secretion from a few thousand hypothalamic neurons. Recent findings have indicated that the neuroendocrine control of ... -
Gene-educational attainment interactions in a multi-ancestry genome-wide meta-analysis identify novel blood pressure loci.
de Las Fuentes, L; Sung, YJ; Noordam, R; Winkler, T; Feitosa, MF; Schwander, K; Bentley, AR; Brown, MR; Guo, X; Manning, A (Springer Nature, 2020-05-05)Educational attainment is widely used as a surrogate for socioeconomic status (SES). Low SES is a risk factor for hypertension and high blood pressure (BP). To identify novel BP loci, we performed multi-ancestry meta-analyses ... -
Genetic architecture of left ventricular phenotypes derived from 17,000 CMR studies in the UK Biobank population imaging cohort
Aung, N; Vargas, JD; Manichaikul, AW; Yang, C; Cabrera, CP; Warren, HR; Fung, K; Tzanis, E; Barnes, MR; Bluemke, DA (2019-06) -
Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk (vol 49, pg 403, 2017)
Warren, HR; Evangelou, E; Cabrera, CP; Gao, H; Ren, M; Mifsud, B; Ntalla, I; Surendran, P; Liu, C; Cook, JP (2017-10) -
Genome-Wide Association Study of Blood Pressure Traits by Hispanic/Latino Background: the Hispanic Community Health Study/Study of Latinos
Sofer, T; Wong, Q; Hartwig, FP; Taylor, K; Warren, HR; Evangelou, E; Cabrera, CP; Levy, D; Kramer, H; Lange, LA (2017-09-04) -
Heritability and genotypic correlation of CMR-derived LV phenotypes in the UK Biobank population imaging study
Aung, N; Vargas, JD; Manichaikul, AW; Yang, CP; Cabrera, CP; Warren, HR; Fung, K; Tzanis, E; Barnes, MR; Piechnik, SK (2019-06) -
Hypertension genetics past, present and future applications
Olczak, KJ; Taylor-Bateman, V; Nicholls, HL; Traylor, M; Cabrera, CP; Munroe, PB (2021) -
A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure
Sung, YJ; Winkler, TW; de las Fuentes, L; Bentley, AR; Brown, MR; Kraja, AT; Schwander, K; Ntalla, I; Guo, X; Franceschini, N (2018-03-01) -
Multi-trait genome-wide association analysis of blood pressure identifies 45 additional loci
Cabrera, CP; Pazoki, R; Giri, A; Hellwege, JN; Evangelou, E; Ramirez, J; Wain, LV; Tzoulaki, I; Edwards, TL; Elliott, P (2020-12) -
New Blood Pressure-Associated Loci Identified in Meta-Analyses of 475000 Individuals
Kraja, AT; Cook, JP; Warren, HR; Surendran, P; Liu, C; Evangelou, E; Manning, AK; Grarup, N; Drenos, F; Sim, X (American Heart Association, 2017-10-13)Background— Genome-wide association studies have recently identified >400 loci that harbor DNA sequence variants that influence blood pressure (BP). Our earlier studies identified and validated 56 single nucleotide variants ... -
Novel Blood Pressure Locus and Gene Discovery Using Genome-Wide Association Study and Expression Data Sets From Blood and the Kidney
Wain, LV; Vaez, A; Jansen, R; Joehanes, R; van der Most, PJ; Erzurumluoglu, AM; O'Reilly, PF; Cabrera, CP; Warren, HR; Rose, LM (2017-09)