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dc.contributor.authorNibali, Len_US
dc.date.accessioned2018-01-29T15:50:59Z
dc.date.available2016-10-01en_US
dc.date.issued2018-02en_US
dc.date.submitted2017-12-21T11:44:47.565Z
dc.identifier.urihttp://qmro.qmul.ac.uk/xmlui/handle/123456789/31804
dc.description.abstractTooth eruption is characterized by a concert of mechanisms that result in the emergence of teeth in the oral cavity. Genetic variants seem to regulate this process and the formation of a gingival sulcus around the teeth. Interindividual variability in the response to microbial triggers in the sulcus plays an important role in the onset and progression of periodontal diseases. Host genetic variants can influence this variability, affecting the response of the host to the subgingival biofilm. Genetic factors affecting tooth eruption could potentially influence susceptibility to periodontal diseases and, specifically, susceptibility to localized aggressive periodontitis. This review aims to discuss the evidence available for the role of host genetic variants in tooth eruption and to and to give some directions for prospective research in this topic.en_US
dc.format.extent35 - 42en_US
dc.languageengen_US
dc.language.isoenen_US
dc.relation.ispartofPeriodontol 2000en_US
dc.rights"This is the peer reviewed version of the following article: Nibali, L. (2017), Development of the gingival sulcus at the time of tooth eruption and the influence of genetic factors. Periodontol 2000, 76: 35–42. doi:10.1111/prd.12158 which has been published in final form at https://doi.org/10.1111/prd.12158 . This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Self-Archiving."
dc.subjectAggressive Periodontitisen_US
dc.subjectBiofilmsen_US
dc.subjectDisease Progressionen_US
dc.subjectGenetic Locien_US
dc.subjectGenetic Variationen_US
dc.subjectGingivaen_US
dc.subjectHumansen_US
dc.subjectPeriodontal Diseasesen_US
dc.subjectPeriodontitisen_US
dc.subjectTooth Eruptionen_US
dc.subjectTooth Migrationen_US
dc.subjectTooth Rooten_US
dc.titleDevelopment of the gingival sulcus at the time of tooth eruption and the influence of genetic factors.en_US
dc.typeArticle
dc.identifier.doi10.1111/prd.12158en_US
pubs.author-urlhttps://www.ncbi.nlm.nih.gov/pubmed/29193355en_US
pubs.issue1en_US
pubs.notesNot knownen_US
pubs.publication-statusPublisheden_US
pubs.volume76en_US


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