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    Development of the gingival sulcus at the time of tooth eruption and the influence of genetic factors. 
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    • Development of the gingival sulcus at the time of tooth eruption and the influence of genetic factors.
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    • Centre for Oral Immunobiology and Regenerative Medicine
    • Development of the gingival sulcus at the time of tooth eruption and the influence of genetic factors.
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    Development of the gingival sulcus at the time of tooth eruption and the influence of genetic factors.

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    Accepted version (49.43Kb)
    Volume
    76
    Pagination
    35 - 42
    DOI
    10.1111/prd.12158
    Journal
    Periodontol 2000
    Issue
    1
    Metadata
    Show full item record
    Abstract
    Tooth eruption is characterized by a concert of mechanisms that result in the emergence of teeth in the oral cavity. Genetic variants seem to regulate this process and the formation of a gingival sulcus around the teeth. Interindividual variability in the response to microbial triggers in the sulcus plays an important role in the onset and progression of periodontal diseases. Host genetic variants can influence this variability, affecting the response of the host to the subgingival biofilm. Genetic factors affecting tooth eruption could potentially influence susceptibility to periodontal diseases and, specifically, susceptibility to localized aggressive periodontitis. This review aims to discuss the evidence available for the role of host genetic variants in tooth eruption and to and to give some directions for prospective research in this topic.
    Authors
    Nibali, L
    URI
    http://qmro.qmul.ac.uk/xmlui/handle/123456789/31804
    Collections
    • Centre for Oral Immunobiology and Regenerative Medicine [417]
    Language
    eng
    Licence information
    "This is the peer reviewed version of the following article: Nibali, L. (2017), Development of the gingival sulcus at the time of tooth eruption and the influence of genetic factors. Periodontol 2000, 76: 35–42. doi:10.1111/prd.12158 which has been published in final form at https://doi.org/10.1111/prd.12158 . This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Self-Archiving."
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