Browsing Wolfson Institute of Preventive Medicine by Author "Zai, CC"
Now showing items 1-8 of 8
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Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects
Marshall, CR; Marshall, CR; Howrigan, DP; Merico, D; Thiruvahindrapuram, B; Wu, W; Greer, DS; Antaki, D; Shetty, A; Holmans, PA (2017-01) -
Dissecting the Shared Genetic Architecture of Suicide Attempt, Psychiatric Disorders, and Known Risk Factors
Mullins, N; Kang, J; Campos, AI; Coleman, JRI; Edwards, AC; Galfalvy, H; Levey, DF; Lori, A; Shabalin, A; Starnawska, A (2022-02-01) -
Gene expression imputation across multiple brain regions provides insights into schizophrenia risk
Huckins, LM; Dobbyn, A; Ruderfer, DM; Hoffman, G; Wang, W; Pardinas, AF; Rajagopal, VM; Als, TD; Nguyen, HT; Girdhar, K (Springer Nature, 2019-03-25)Transcriptomic imputation approaches combine eQTL reference panels with large-scale genotype data in order to test associations between disease and gene expression. These genic associations could elucidate signals in complex ... -
Genome-wide association study of suicidal behaviour severity in mood disorders.
Zai, CC; Fabbri, C; Hosang, GM; Zhang, RS; Koyama, E; de Luca, V; Tiwari, AK; King, N; Strauss, J; Jones, I (2021-03-30)OBJECTIVE: Suicide is a major public health problem and it has a prominent genetic component. We performed a genome-wide association study (GWAS) of suicidal behaviour severity. METHODS: Suicide behaviour severity was ... -
A genome-wide association study of suicide severity scores in bipolar disorder
Zai, CC; Goncalves, VF; Tiwari, AK; Gagliano, SA; Hosang, G; de Luca, V; Shaikh, SA; King, N; Chen, Q; Xu, W (2015-06) -
Genomic Relationships, Novel Loci, and Pleiotropic Mechanisms across Eight Psychiatric Disorders
Lee, PH; Anttila, V; Won, H; Feng, Y-CA; Rosenthal, J; Zhu, Z; Tucker-Drob, EM; Nivard, MG; Grotzinger, AD; Posthuma, D (2019-12-12) -
Interplay between polygenic risk for mood disorders and stressful life events in bipolar disorder.
Hosang, GM; Shakoor, S; King, N; Sanches, M; Vincent, JB; Kennedy, JL; McGuffin, P; Keers, R; Zai, CC (Elsevier, 2024-01-19)BACKGROUND: Although genetic and environmental factors are involved in the aetiology of bipolar disorder [BD], studies focused on their interplay are lacking. The current investigation examines interactions and correlations ... -
Mapping genomic loci implicates genes and synaptic biology in schizophrenia
Trubetskoy, V; Pardinas, AF; Qi, T; Panagiotaropoulou, G; Awasthi, S; Bigdeli, TB; Bryois, J; Chen, C-Y; Dennison, CA; Hall, LS (2022)