Browsing Wolfson Institute of Preventive Medicine by Author "Zagorac, S"
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DNMT1 Inhibition Reprograms Pancreatic Cancer Stem Cells via Upregulation of the miR-17-92 Cluster.
Zagorac, S; Alcala, S; Fernandez Bayon, G; Bou Kheir, T; Schoenhals, M; González-Neira, A; Fernandez Fraga, M; Aicher, A; Heeschen, C; Sainz, B (2016-08-01)Pancreatic ductal adenocarcinoma (PDAC) and other carcinomas are hierarchically organized, with cancer stem cells (CSC) residing at the top of the hierarchy, where they drive tumor progression, metastasis, and chemoresistance. ...