Browsing Wolfson Institute of Preventive Medicine by Author "Williams, NM"
Now showing items 1-7 of 7
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Additional rare variant analysis in Parkinson’s disease cases with and without known pathogenic mutations: evidence for oligogenic inheritance
Lubbe, SJ; Escott-Price, V; Gibbs, JR; Nalls, MA; Bras, J; Price, TR; Nicolas, A; Jansen, IE; Mok, KY; Pittman, AMOligogenic inheritance implies a role for several genetic factors in disease etiology. We studied oligogenic inheritance in Parkinson’s (PD) by assessing the potential burden of additional rare variants in established ... -
Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects
Marshall, CR; Marshall, CR; Howrigan, DP; Merico, D; Thiruvahindrapuram, B; Wu, W; Greer, DS; Antaki, D; Shetty, A; Holmans, PA (2017-01) -
Deletions at 22q11.2 in idiopathic Parkinson's disease: a combined analysis of genome-wide association data
Mok, KY; Sheerin, U; Simón-Sánchez, J; Salaka, A; Chester, L; Escott-Price, V; Mantripragada, K; Doherty, KM; Noyce, AJ; Mencacci, NE (2016-05) -
Diagnosis of Parkinson's disease on the basis of clinical and genetic classification: a population-based modelling study
Nalls, MA; McLean, CY; Rick, J; Eberly, S; Hutten, SJ; Gwinn, K; Sutherland, M; Martinez, M; Heutink, P; Williams, NM (Elsevier BV, 2015-10) -
Gene expression imputation across multiple brain regions provides insights into schizophrenia risk
Huckins, LM; Dobbyn, A; Ruderfer, DM; Hoffman, G; Wang, W; Pardinas, AF; Rajagopal, VM; Als, TD; Nguyen, HT; Girdhar, K (Springer Nature, 2019-03-25)Transcriptomic imputation approaches combine eQTL reference panels with large-scale genotype data in order to test associations between disease and gene expression. These genic associations could elucidate signals in complex ... -
Genomic Relationships, Novel Loci, and Pleiotropic Mechanisms across Eight Psychiatric Disorders
Lee, PH; Anttila, V; Won, H; Feng, Y-CA; Rosenthal, J; Zhu, Z; Tucker-Drob, EM; Nivard, MG; Grotzinger, AD; Posthuma, D (2019-12-12) -
Mapping genomic loci implicates genes and synaptic biology in schizophrenia
Trubetskoy, V; Pardinas, AF; Qi, T; Panagiotaropoulou, G; Awasthi, S; Bigdeli, TB; Bryois, J; Chen, C-Y; Dennison, CA; Hall, LS (2022)