Browsing Wolfson Institute of Preventive Medicine by Author "Weil, RS"
Now showing items 1-5 of 5
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Eligibility for antiamyloid treatment: preparing for disease-modifying therapies for Alzheimer's disease.
Dobson, R; Patterson, K; Malik, R; Mandal, U; Asif, H; Humphreys, R; Payne, M; O-Charoenrat, E; Huzzey, L; Clare, A (BMJ Publishing Group, 2024-06-11)BACKGROUND: Disease-modifying therapies (DMTs) for Alzheimer's disease (AD) have early evidence of efficacy. Widespread delivery of DMTs will require major service reconfiguration. Treatment pathways will need to include ... -
Embedding Patient Input in Outcome Measures for Long-Term Disease-Modifying Parkinson Disease Trials.
Gonzalez-Robles, C; Bartlett, M; Burnell, M; Clarke, CS; Haar, S; Hu, MT; Huxford, B; Jha, A; Lawton, M; Noyce, A (2023-12-22)BACKGROUND: Clinical trials of disease-modifying therapies in PD require valid and responsive primary outcome measures that are relevant to patients. OBJECTIVES: The objective is to select a patient-centered primary outcome ... -
Outcome Measures for Disease-Modifying Trials in Parkinson's Disease: Consensus Paper by the EJS ACT-PD Multi-Arm Multi-Stage Trial Initiative
Gonzalez-Robles, C; Weil, RS; van Wamelen, D; Bartlett, M; Burnell, M; Clarke, CS; Hu, MT; Huxford, B; Jha, A; Lambert, C (2023) -
Processing of Degraded Speech in Brain Disorders
Jiang, J; Benhamou, E; Waters, S; Johnson, JCS; Volkmer, A; Weil, RS; Marshall, CR; Warren, JD; Hardy, CJDThe speech we hear every day is typically “degraded” by competing sounds and the idiosyncratic vocal characteristics of individual speakers. While the comprehension of “degraded” speech is normally automatic, it depends ... -
Suspecting dementia: canaries, chameleons and zebras.
Johnson, JCS; McWhirter, L; Hardy, CJD; Crutch, SJ; Marshall, CR; Mummery, CJ; Rohrer, JD; Rossor, MN; Schott, JM; Weil, RS (2021-07-02)The early and accurate diagnosis of dementia is more important than ever before but remains challenging. Dementia is increasingly the business of neurologists and, with ageing populations worldwide, will become even more ...