Browsing Wolfson Institute of Preventive Medicine by Author "Walters, JTR"
Now showing items 1-9 of 9
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Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects
Marshall, CR; Marshall, CR; Howrigan, DP; Merico, D; Thiruvahindrapuram, B; Wu, W; Greer, DS; Antaki, D; Shetty, A; Holmans, PA (2017-01) -
The contribution of rare variants to risk of schizophrenia in individuals with and without intellectual disability
Singh, T; Walters, JTR; Johnstone, M; Curtis, D; Suvisaari, J; Torniainen, M; Rees, E; Iyegbe, C; Blackwood, D; McIntosh, AM (2017-08) -
Dissecting the Shared Genetic Architecture of Suicide Attempt, Psychiatric Disorders, and Known Risk Factors
Mullins, N; Kang, J; Campos, AI; Coleman, JRI; Edwards, AC; Galfalvy, H; Levey, DF; Lori, A; Shabalin, A; Starnawska, A (2022-02-01) -
Exome sequencing in bipolar disorder identifies AKAP11 as a risk gene shared with schizophrenia
Palmer, DS; Howrigan, DP; Chapman, SB; Adolfsson, R; Bass, N; Blackwood, D; Boks, MPM; Chen, C-Y; Churchhouse, C; Corvin, AP (2022) -
Gene expression imputation across multiple brain regions provides insights into schizophrenia risk
Huckins, LM; Dobbyn, A; Ruderfer, DM; Hoffman, G; Wang, W; Pardinas, AF; Rajagopal, VM; Als, TD; Nguyen, HT; Girdhar, K (Springer Nature, 2019-03-25)Transcriptomic imputation approaches combine eQTL reference panels with large-scale genotype data in order to test associations between disease and gene expression. These genic associations could elucidate signals in complex ... -
Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology
Mullins, N; Forstner, AJ; O'Connell, KS; Coombes, B; Coleman, JRI; Qiao, Z; Als, TD; Bigdeli, TB; Borte, S; Bryois, J (2021-05-17) -
Genomic Relationships, Novel Loci, and Pleiotropic Mechanisms across Eight Psychiatric Disorders
Lee, PH; Anttila, V; Won, H; Feng, Y-CA; Rosenthal, J; Zhu, Z; Tucker-Drob, EM; Nivard, MG; Grotzinger, AD; Posthuma, D (2019-12-12) -
Interaction Testing and Polygenic Risk Scoring to Estimate the Association of Common Genetic Variants With Treatment Resistance in Schizophrenia.
Pardiñas, AF; Smart, SE; Willcocks, IR; Holmans, PA; Dennison, CA; Lynham, AJ; Legge, SE; Baune, BT; Bigdeli, TB; Cairns, MJ (2022-03-01)Importance: About 20% to 30% of people with schizophrenia have psychotic symptoms that do not respond adequately to first-line antipsychotic treatment. This clinical presentation, chronic and highly disabling, is known as ... -
Mapping genomic loci implicates genes and synaptic biology in schizophrenia
Trubetskoy, V; Pardinas, AF; Qi, T; Panagiotaropoulou, G; Awasthi, S; Bigdeli, TB; Bryois, J; Chen, C-Y; Dennison, CA; Hall, LS (2022)