Browsing Wolfson Institute of Preventive Medicine by Author "Tylee, DS"

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    • A polygenic resilience score moderates the genetic risk for schizophrenia. 

      Hess, JL; Tylee, DS; Mattheisen, M; Schizophrenia Working Group of the Psychiatric Genomics Consortium; Lundbeck Foundation Initiative for Integrative Psychiatric Research (iPSYCH); Børglum, AD; Als, TD; Grove, J; Werge, T; Mortensen, PB (2019-09-06)
      Based on the discovery by the Resilience Project (Chen R. et al. Nat Biotechnol 34:531-538, 2016) of rare variants that confer resistance to Mendelian disease, and protective alleles for some complex diseases, we posited ...