Browsing Wolfson Institute of Preventive Medicine by Author "St Clair, D"
Now showing items 1-7 of 7
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Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects
Marshall, CR; Marshall, CR; Howrigan, DP; Merico, D; Thiruvahindrapuram, B; Wu, W; Greer, DS; Antaki, D; Shetty, A; Holmans, PA (2017-01) -
Exome sequencing in bipolar disorder identifies AKAP11 as a risk gene shared with schizophrenia
Palmer, DS; Howrigan, DP; Chapman, SB; Adolfsson, R; Bass, N; Blackwood, D; Boks, MPM; Chen, C-Y; Churchhouse, C; Corvin, AP (2022) -
Gene expression imputation across multiple brain regions provides insights into schizophrenia risk
Huckins, LM; Dobbyn, A; Ruderfer, DM; Hoffman, G; Wang, W; Pardinas, AF; Rajagopal, VM; Als, TD; Nguyen, HT; Girdhar, K (Springer Nature, 2019-03-25)Transcriptomic imputation approaches combine eQTL reference panels with large-scale genotype data in order to test associations between disease and gene expression. These genic associations could elucidate signals in complex ... -
Genome-wide association study identifies 30 loci associated with bipolar disorder
Stahl, EA; Breen, G; Forstner, AJ; McQuillin, A; Ripke, S; Trubetskoy, V; Mattheisen, M; Wang, Y; Coleman, JRI; Gaspar, HA (2019-05) -
Interaction Testing and Polygenic Risk Scoring to Estimate the Association of Common Genetic Variants With Treatment Resistance in Schizophrenia.
Pardiñas, AF; Smart, SE; Willcocks, IR; Holmans, PA; Dennison, CA; Lynham, AJ; Legge, SE; Baune, BT; Bigdeli, TB; Cairns, MJ (2022-03-01)Importance: About 20% to 30% of people with schizophrenia have psychotic symptoms that do not respond adequately to first-line antipsychotic treatment. This clinical presentation, chronic and highly disabling, is known as ... -
Mapping genomic loci implicates genes and synaptic biology in schizophrenia
Trubetskoy, V; Pardinas, AF; Qi, T; Panagiotaropoulou, G; Awasthi, S; Bigdeli, TB; Bryois, J; Chen, C-Y; Dennison, CA; Hall, LS (2022) -
Rare coding variants in ten genes confer substantial risk for schizophrenia
Singh, T; Poterba, T; Curtis, D; Akil, H; Al Eissa, M; Barchas, JD; Bass, N; Bigdeli, TB; Breen, G; Bromet, EJ (2022)