Browsing Wolfson Institute of Preventive Medicine by Author "Purcell, SM"
Now showing items 1-5 of 5
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Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects
Marshall, CR; Marshall, CR; Howrigan, DP; Merico, D; Thiruvahindrapuram, B; Wu, W; Greer, DS; Antaki, D; Shetty, A; Holmans, PA (2017-01) -
Gene expression imputation across multiple brain regions provides insights into schizophrenia risk
Huckins, LM; Dobbyn, A; Ruderfer, DM; Hoffman, G; Wang, W; Pardinas, AF; Rajagopal, VM; Als, TD; Nguyen, HT; Girdhar, K (Springer Nature, 2019-03-25)Transcriptomic imputation approaches combine eQTL reference panels with large-scale genotype data in order to test associations between disease and gene expression. These genic associations could elucidate signals in complex ... -
Genome-wide association study identifies 30 loci associated with bipolar disorder
Stahl, EA; Breen, G; Forstner, AJ; McQuillin, A; Ripke, S; Trubetskoy, V; Mattheisen, M; Wang, Y; Coleman, JRI; Gaspar, HA (2019-05) -
Identifying relationships among genomic disease regions: predicting genes at pathogenic SNP associations and rare deletions.
Raychaudhuri, S; Plenge, RM; Rossin, EJ; Ng, ACY; International Schizophrenia Consortium; Purcell, SM; Sklar, P; Scolnick, EM; Xavier, RJ; Altshuler, D (2009-06)Translating a set of disease regions into insight about pathogenic mechanisms requires not only the ability to identify the key disease genes within them, but also the biological relationships among those key genes. Here ... -
Psychiatric genome-wide association study analyses implicate neuronal, immune and histone pathways
O'Dushlaine, C; Rossin, L; Lee, PH; Duncan, L; Parikshak, NN; Newhouse, S; Ripke, S; Neale, BM; Purcell, SM; Posthuma, D (2015-02)