Browsing Wolfson Institute of Preventive Medicine by Author "NOYCE, AJ"
Now showing items 1-10 of 10
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Assessing cognitive dysfunction in Parkinson’s: An online tool to detect visuo-perceptual deficits
NOYCE, AJ (Wiley, 2018-02-23) -
Change in Mortality of Generalized Convulsive Status Epilepticus in High-Income Countries Over Time. A Systematic Review and Meta-analysis
NOYCE, AJ; Neligan, A; Gosavi, TD; Shorvon, SD; Köhler, S; Walker, MC (American Medical Association, 2019-05-28) -
Mendelian randomization study shows no causal relationship between circulating urate levels and Parkinson’s disease.
NOYCE, AJ (Wiley, 2018-07-16) -
Parkinson's disease age at onset genome‐wide association study: Defining heritability, genetic loci, and α‐synuclein mechanisms
NOYCE, AJ; International Parkinson's Disease Genomics Consortium (IPDGC) (Wiley, 2019-04-07)Background: Increasing evidence supports an extensive and complex genetic contribution to PD. Previous genome‐wide association studies (GWAS) have shed light on the genetic basis of risk for this disease. However, the ... -
Parkinson's disease age at onset genome‐wide association study: Defining heritability, genetic loci, and α‐synuclein mechanisms
NOYCE, AJ; International Parkinson's Disease Genomics Consortium (IPDGC) (Wiley, 2019-04-07)Background: Increasing evidence supports an extensive and complex genetic contribution to PD. Previous genome‐wide association studies (GWAS) have shed light on the genetic basis of risk for this disease. However, the ... -
Predicting Diagnosis of Parkinson’s disease: A Risk Algorithm based on Primary Care presentations
Schrag, A; Anastasiou, Z; Ambler, G; NOYCE, AJ; walters, K (Wiley Periodicals, Inc. on behalf of International Parkinson and Movement Disorder Society, 2019-02-08)BACKGROUND: Diagnosis of Parkinson's disease (PD) is typically preceded by nonspecific presentations in primary care. OBJECTIVES: The objective of this study was to develop and validate a prediction model for diagnosis ... -
The prodromes of Parkinson's disease.
NOYCE, AJ; Rees, R; Schrag, A (Wiley, 2018-11-17)Whilst the diagnosis of Parkinson’s disease (PD) relies on the motor triad of bradyki-nesia, rigidity and tremor, the underlying pathological process starts many years be-fore these signs are overt. In this prodromal phase ... -
Shared polygenic risk and causal inferences in amyotrophic lateral sclerosis
NOYCE, AJ; Bandres‐Ciga, S; Hemani, G; Nicolas, N; Calvo, A; Mora, G; The ITALSGEN Consortium; The International ALS Genomics Consortium; Tienari, P; Stone, D (Wiley, 2019-02-05)Objective: To identify shared polygenic risk and causal associations in amyotrophic lateral sclerosis (ALS). Methods: Linkage disequilibrium score regression and Mendelian randomization were applied in a large‐scale, ...