Browsing Wolfson Institute of Preventive Medicine by Author "Kahn, RS"
Now showing items 1-11 of 11
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Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects
Marshall, CR; Marshall, CR; Howrigan, DP; Merico, D; Thiruvahindrapuram, B; Wu, W; Greer, DS; Antaki, D; Shetty, A; Holmans, PA (2017-01) -
Dissecting the Shared Genetic Architecture of Suicide Attempt, Psychiatric Disorders, and Known Risk Factors
Mullins, N; Kang, J; Campos, AI; Coleman, JRI; Edwards, AC; Galfalvy, H; Levey, DF; Lori, A; Shabalin, A; Starnawska, A (2022-02-01) -
Exome sequencing in bipolar disorder identifies AKAP11 as a risk gene shared with schizophrenia
Palmer, DS; Howrigan, DP; Chapman, SB; Adolfsson, R; Bass, N; Blackwood, D; Boks, MPM; Chen, C-Y; Churchhouse, C; Corvin, AP (2022) -
Gene expression imputation across multiple brain regions provides insights into schizophrenia risk
Huckins, LM; Dobbyn, A; Ruderfer, DM; Hoffman, G; Wang, W; Pardinas, AF; Rajagopal, VM; Als, TD; Nguyen, HT; Girdhar, K (Springer Nature, 2019-03-25)Transcriptomic imputation approaches combine eQTL reference panels with large-scale genotype data in order to test associations between disease and gene expression. These genic associations could elucidate signals in complex ... -
Genetic correlation between amyotrophic lateral sclerosis and schizophrenia.
McLaughlin, RL; Schijven, D; van Rheenen, W; van Eijk, KR; O'Brien, M; Kahn, RS; Ophoff, RA; Goris, A; Bradley, DG; Al-Chalabi, A (2017-03-21)We have previously shown higher-than-expected rates of schizophrenia in relatives of patients with amyotrophic lateral sclerosis (ALS), suggesting an aetiological relationship between the diseases. Here, we investigate the ... -
Genome-wide association study identifies 30 loci associated with bipolar disorder
Stahl, EA; Breen, G; Forstner, AJ; McQuillin, A; Ripke, S; Trubetskoy, V; Mattheisen, M; Wang, Y; Coleman, JRI; Gaspar, HA (2019-05) -
Genome-wide association study of borderline personality disorder reveals genetic overlap with bipolar disorder, major depression and schizophrenia
Witt, SH; Streit, F; Jungkunz, M; Frank, J; Awasthi, S; Reinbold, CS; Treutlein, J; Degenhardt, F; Forstner, AJ; Heilmann-Heimbach, S (2017-06-20) -
Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology
Mullins, N; Forstner, AJ; O'Connell, KS; Coombes, B; Coleman, JRI; Qiao, Z; Als, TD; Bigdeli, TB; Borte, S; Bryois, J (2021-05-17) -
Mapping genomic loci implicates genes and synaptic biology in schizophrenia
Trubetskoy, V; Pardinas, AF; Qi, T; Panagiotaropoulou, G; Awasthi, S; Bigdeli, TB; Bryois, J; Chen, C-Y; Dennison, CA; Hall, LS (2022) -
Psychiatric genome-wide association study analyses implicate neuronal, immune and histone pathways
O'Dushlaine, C; Rossin, L; Lee, PH; Duncan, L; Parikshak, NN; Newhouse, S; Ripke, S; Neale, BM; Purcell, SM; Posthuma, D (2015-02) -
Rare coding variants in ten genes confer substantial risk for schizophrenia
Singh, T; Poterba, T; Curtis, D; Akil, H; Al Eissa, M; Barchas, JD; Bass, N; Bigdeli, TB; Breen, G; Bromet, EJ (2022)