Browsing Wolfson Institute of Preventive Medicine by Author "Evans, DG"
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505 Attitudes towards risk reducing early salpingectomy with delayed oophorectomy for ovarian cancer prevention: a cohort study
Gaba, F; Blyuss, O; Legood, R; Izatt, L; Tripathi, V; Ragupathy, K; Crawfordd, R; Evans, DG; Menon, U; Manchanda, R (BMJ, 2020-12-04)Abstract 505 from ESGO SoA 2020 Conference Abstracts. [Abstract only] -
Attitudes towards risk-reducing early salpingectomy with delayed oophorectomy for ovarian cancer prevention: a cohort study
Gaba, F; Blyuss, O; Chandrasekaran, D; Osman, M; Goyal, S; Gan, C; Izatt, L; Tripathi, V; Esteban, I; McNicol, L (2020-08-16) -
The avoiding late diagnosis of ovarian cancer (ALDO) project; a pilot national surveillance programme for women with pathogenic germline variants in BRCA1 and BRCA2
Philpott, S; Raikou, M; Manchanda, R; Lockley, M; Singh, N; Scott, M; Evans, DG; Adlard, J; Ahmed, M; Edmondson, R (2023) -
Breast cancer risk in a screening cohort of Asian and white British/Irish women from Manchester UK.
Evans, DG; Brentnall, AR; Harvie, M; Astley, S; Harkness, EF; Stavrinos, P; Donnelly, LS; Sampson, S; Idries, F; Watterson, D (2018-01-25)BACKGROUND: The differences between breast cancer risk factors in white British/Irish and Asian women attending screening in the UK are not well documented. METHODS: Between 2009-15 ethnicity and traditional breast cancer ... -
A comparison of five methods of measuring mammographic density: a case-control study
Astley, SM; Harkness, EF; Sergeant, JC; Warwick, J; Stavrinos, P; Warren, R; Wilson, M; Beetles, U; Gadde, S; Lim, Y (2018-02-05) -
Cost-Effectiveness of Gene-Specific Prevention Strategies for Ovarian and Breast Cancer.
Wei, X; Sun, L; Slade, E; Fierheller, CT; Oxley, S; Kalra, A; Sia, J; Sideris, M; McCluggage, WG; Bromham, N (2024-02-05)IMPORTANCE: Pathogenic variants (PVs) in BRCA1, BRCA2, PALB2, RAD51C, RAD51D, and BRIP1 cancer susceptibility genes (CSGs) confer an increased ovarian cancer (OC) risk, with BRCA1, BRCA2, PALB2, RAD51C, and RAD51D PVs also ... -
Distribution of breast cancer risk from SNPs and classical risk factors in women of routine screening age in the UK
Brentnall, AR; Evans, DG; Cuzick, J (2014-02-04) -
EE675 Cost-Effectiveness Analysis of Cancer Susceptibility Gene-Specific Prevention and Surveillance Strategies for Ovarian and Breast Cancer
Wei, X; Sun, L; Slade, E; Oxley, S; Kalra, A; Sia, J; Sideris, M; Fierheller, C; Brentnall, A; Duffy, S (Elsevier, 2023-12) -
Effect of baseline oestradiol serum concentration on the efficacy of anastrozole for preventing breast cancer in postmenopausal women at high risk: a case-control study of the IBIS-II prevention trial
Cuzick, J; Chu, K; Keevil, B; Brentnall, AR; Howell, A; Zdenkowski, N; Bonanni, B; Loibl, S; Holli, K; Evans, DG (Elsevier, 2023-12-06)Background An increased risk of breast cancer is associated with high serum concentrations of oestradiol and testosterone in postmenopausal women, but little is known about how these hormones affect response to endocrine ... -
Exploring the prediction performance for breast cancer risk based on volumetric mammographic density at different thresholds
Wang, C; Brentnall, AR; Cuzick, J; Harkness, EF; Evans, DG; Astley, S (2018-06-08) -
Final Results of the Prospective FH02 Mammographic Surveillance Study of Women Aged 35-39 at Increased Familial Risk of Breast Cancer.
Evans, DG; Thomas, S; Caunt, J; Burch, A; Brentnall, AR; Roberts, L; Howell, A; Wilson, M; Fox, R; Hillier, S (2019-01)Background: Many women who are at increased risk of breast cancer due to a mother or sister diagnosed with breast cancer aged under 40 do not currently qualify for surveillance before 40 years of age. There are almost no ... -
Genome-wide association study of germline variants and breast cancer-specific mortality.
Escala-Garcia, M; Guo, Q; Dörk, T; Canisius, S; Keeman, R; Dennis, J; Beesley, J; Lecarpentier, J; Bolla, MK; Wang, Q (Nature Publishing Group, 2019-02-21)BACKGROUND: We examined the associations between germline variants and breast cancer mortality using a large meta-analysis of women of European ancestry. METHODS: Meta-analyses included summary estimates based on Cox models ... -
The impact of a panel of 18 SNPs on breast cancer risk in women attending a UK familial screening clinic: a case-control study
Evans, DG; Brentnall, A; Byers, H; Harkness, E; Stavrinos, P; Howell, A; Newman, WG; Cuzick, J; Grp, F-RS (2017-02) -
The impact of using weight estimated from mammographic images vs self-reported weight on breast cancer risk calculation
Nair, KP; Harkness, EF; Gadde, S; Lim, YY; Maxwell, AJ; Moschidis, E; Foden, P; Cuzick, J; Brentnall, A; Evans, DG (2017) -
Implementation of Multigene Germline and Parallel Somatic Genetic Testing in Epithelial Ovarian Cancer: SIGNPOST Study.
Chandrasekaran, D; Sobocan, M; Blyuss, O; Miller, RE; Evans, O; Crusz, SM; Mills-Baldock, T; Sun, L; Hammond, RFL; Gaba, F (MDPI, 2021-08-27)We present findings of a cancer multidisciplinary-team (MDT) coordinated mainstreaming pathway of unselected 5-panel germline BRCA1/BRCA2/RAD51C/RAD51D/BRIP1 and parallel somatic BRCA1/BRCA2 testing in all women with ... -
The importance of ethnicity: Are breast cancer polygenic risk scores ready for women who are not of White European origin?
Evans, DG; van Veen, EM; Byers, H; Roberts, E; Howell, A; Howell, SJ; Harkness, EF; Brentnall, A; Cuzick, J; Newman, WG (Wiley, 2021-08-30)Polygenic risk scores (PRS) for disease risk stratification show great promise for application in general populations, but most are based on data from individuals of White European origin. We assessed two well validated ... -
Is Breast Cancer Risk Associated with Menopausal Hormone Therapy Modified by Current or Early Adulthood BMI or Age of First Pregnancy?
Leventea, E; Harkness, EF; Brentnall, AR; Howell, A; Evans, DG; Harvie, M (2021) -
Lifestyle behaviours and health measures of women at increased risk of breast cancer taking chemoprevention.
Pegington, M; Evans, DG; Howell, A; Donnelly, LS; Wiseman, J; Cuzick, JM; Harvie, MN (Lippincott, Williams & Wilkins, 2018-11-15)Women at increased breast cancer (BC) risk are eligible for chemoprevention. Healthy lifestyles are potentially important for these women to improve efficacy and minimise side effects of chemoprevention and reduce the risk ... -
Mammographic density change in a cohort of premenopausal women receiving tamoxifen for breast cancer prevention over 5 years
Brentnall, AR; Warren, R; Harkness, EF; Astley, SM; Wiseman, J; Fox, J; Fox, L; Eriksson, M; Hall, P; Cuzick, J (2020-09-29) -
A novel and fully automated mammographic texture analysis for risk prediction: results from two case-control studies
Wang, C; Brentnall, AR; Cuzick, J; Harkness, EF; Evans, DG; Astley, S (2017-10-18)