Browsing Wolfson Institute of Preventive Medicine by Author "Escott-Price, V"
Now showing items 1-9 of 9
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Additional rare variant analysis in Parkinson’s disease cases with and without known pathogenic mutations: evidence for oligogenic inheritance
Lubbe, SJ; Escott-Price, V; Gibbs, JR; Nalls, MA; Bras, J; Price, TR; Nicolas, A; Jansen, IE; Mok, KY; Pittman, AMOligogenic inheritance implies a role for several genetic factors in disease etiology. We studied oligogenic inheritance in Parkinson’s (PD) by assessing the potential burden of additional rare variants in established ... -
Analysis of shared heritability in common disorders of the brain
Anttila, V; Bulik-Sullivan, B; Finucane, HK; Walters, RK; Bras, J; Duncan, L; Escott-Price, V; Falcone, GJ; Gormley, P; Malik, R (2018-06-22) -
Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects
Marshall, CR; Marshall, CR; Howrigan, DP; Merico, D; Thiruvahindrapuram, B; Wu, W; Greer, DS; Antaki, D; Shetty, A; Holmans, PA (2017-01) -
Deletions at 22q11.2 in idiopathic Parkinson's disease: a combined analysis of genome-wide association data
Mok, KY; Sheerin, U; Simón-Sánchez, J; Salaka, A; Chester, L; Escott-Price, V; Mantripragada, K; Doherty, KM; Noyce, AJ; Mencacci, NE (2016-05) -
Gene expression imputation across multiple brain regions provides insights into schizophrenia risk
Huckins, LM; Dobbyn, A; Ruderfer, DM; Hoffman, G; Wang, W; Pardinas, AF; Rajagopal, VM; Als, TD; Nguyen, HT; Girdhar, K (Springer Nature, 2019-03-25)Transcriptomic imputation approaches combine eQTL reference panels with large-scale genotype data in order to test associations between disease and gene expression. These genic associations could elucidate signals in complex ... -
Genome-wide association study identifies 30 loci associated with bipolar disorder
Stahl, EA; Breen, G; Forstner, AJ; McQuillin, A; Ripke, S; Trubetskoy, V; Mattheisen, M; Wang, Y; Coleman, JRI; Gaspar, HA (2019-05) -
Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology
Mullins, N; Forstner, AJ; O'Connell, KS; Coombes, B; Coleman, JRI; Qiao, Z; Als, TD; Bigdeli, TB; Borte, S; Bryois, J (2021-05-17) -
Investigation of Autosomal Genetic Sex Differences in Parkinson's disease.
Blauwendraat, C; Iwaki, H; Makarious, MB; Bandres-Ciga, S; Leonard, H; Grenn, FP; Lake, J; Krohn, L; Tan, M; Kim, JJ (2021-04-26)OBJECTIVE: Parkinson's disease (PD) is a complex neurodegenerative disorder. Males are on average ~ 1.5 times more likely to develop PD compared to females with European ancestry. Over the years genome-wide association ... -
Mapping genomic loci implicates genes and synaptic biology in schizophrenia
Trubetskoy, V; Pardinas, AF; Qi, T; Panagiotaropoulou, G; Awasthi, S; Bigdeli, TB; Bryois, J; Chen, C-Y; Dennison, CA; Hall, LS (2022)