Browsing Wolfson Institute of Preventive Medicine by Author "23andMe Research Team"

Now showing items 1-3 of 3

    • Genetic modifiers of risk and age at onset in GBA associated Parkinson's disease and Lewy body dementia. 

      Blauwendraat, C; Reed, X; Krohn, L; Heilbron, K; Bandres-Ciga, S; Tan, M; Gibbs, JR; Hernandez, DG; Kumaran, R; Langston, R (2020-01-01)
      Parkinson's disease is a genetically complex disorder. Multiple genes have been shown to contribute to the risk of Parkinson's disease, and currently 90 independent risk variants have been identified by genome-wide association ...

    • Multi-ancestry genome-wide association meta-analysis of Parkinson's disease. 

      Kim, JJ; Vitale, D; Otani, DV; Lian, MM; Heilbron, K; 23andMe Research Team; Iwaki, H; Lake, J; Solsberg, CW; Leonard, H (2024-01)
      Although over 90 independent risk variants have been identified for Parkinson's disease using genome-wide association studies, most studies have been performed in just one population at a time. Here we performed a large-scale ...

    • Unhealthy Behaviours and Risk of Parkinson's Disease: A Mendelian Randomisation Study. 

      Heilbron, K; Jensen, MP; Bandres-Ciga, S; Fontanillas, P; Blauwendraat, C; Nalls, MA; Singleton, AB; Smith, GD; Cannon, P; Noyce, AJ (2021-07-15)
      BACKGROUND: Tobacco smoking and alcohol intake have been identified in observational studies as potentially protective factors against developing Parkinson's disease (PD); the impact of body mass index (BMI) on PD risk is ...