Browsing Awaiting Allocation by Subject "Schizosaccharomyces"
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Amino Acids Whose Intracellular Levels Change Most During Aging Alter Chronological Life Span of Fission Yeast.
(Oxford University Press, 2020-11-03)Amino acid deprivation or supplementation can affect cellular and organismal life span, but we know little about the role of concentration changes in free, intracellular amino acids during aging. Here, we determine free ... -
Crosstalk between the mTOR and DNA Damage Response Pathways in Fission Yeast.
(MDPI, 2021-02-02)Cells have developed response systems to constantly monitor environmental changes and accordingly adjust growth, differentiation, and cellular stress programs. The evolutionarily conserved, nutrient-responsive, mechanistic ... -
Genome-wide screens in yeast models towards understanding chronological lifespan regulation.
(Oxford University Press, 2021-03-17)Cellular models such as yeasts are a driving force in biogerontology studies. Their simpler genome, short lifespans and vast genetic and genomics resources make them ideal to characterise pro-ageing and anti-ageing genes ... -
Interplays of AMPK and TOR in Autophagy Regulation in Yeast.
(MDPI, 2023-02-04)Cells survey their environment and need to balance growth and anabolism with stress programmes and catabolism towards maximum cellular bioenergetics economy and survival. Nutrient-responsive pathways, such as the mechanistic ...