Browsing Awaiting Allocation by Author "Sandhar, BS"
Now showing items 1-3 of 3
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B Cell Mobilization, Dissemination, Fine Tuning of Local Antigen Specificity and Isotype Selection in Asthma.
Ohm-Laursen, L; Meng, H; Hoehn, KB; Nouri, N; Jiang, Y; Clouser, C; Johnstone, TG; Hause, R; Sandhar, BS; Upton, NEG (Frontiers Media, 2021-10-14)In order to better understand how the immune system interacts with environmental triggers to produce organ-specific disease, we here address the hypothesis that B and plasma cells are free to migrate through the mucosal ... -
Crystal structures of the human IgD Fab reveal insights into CH1 domain diversity
Davies, AM; Beavil, RL; Barbolov, M; Sandhar, BS; Gould, HJ; Beavil, AJ; Sutton, BJ; McDonnell, JM (Elsevier, 2023-06-01)Antibodies of the IgD isotype remain the least well characterized of the mammalian immunoglobulin isotypes. Here we report three-dimensional structures for the Fab region of IgD, based on four different crystal structures, ... -
Expanding the Anti-Phl p 7 Antibody Toolkit: An Anti-Idiotype Nanobody Inhibitor.
Vester, SK; Davies, AM; Beavil, RL; Sandhar, BS; Beavil, AJ; Gould, HJ; Sutton, BJ; McDonnell, JM (MDPI, 2023-11-16)We have previously produced a toolkit of antibodies, comprising recombinant human antibodies of all but one of the human isotypes, directed against the polcalcin family antigen Phl p 7. In this work, we complete the toolkit ...