Browsing Awaiting Allocation by Author "Rallis, C"
Now showing items 1-9 of 9
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Amino Acids Whose Intracellular Levels Change Most During Aging Alter Chronological Life Span of Fission Yeast.
Rallis, C; Mülleder, M; Smith, G; Au, YZ; Ralser, M; Bähler, J (Oxford University Press, 2020-11-03)Amino acid deprivation or supplementation can affect cellular and organismal life span, but we know little about the role of concentration changes in free, intracellular amino acids during aging. Here, we determine free ... -
Chickens get their place in the sun.
Rallis, C (BMC, 2007-05-25)A report on the International Chick Meeting 'The Chick as a Model Organism: Genes, Development and Function', Barcelona, Spain, 11-14 April 2007. -
Crosstalk between the mTOR and DNA Damage Response Pathways in Fission Yeast.
Alao, J-P; Legon, L; Rallis, C (MDPI, 2021-02-02)Cells have developed response systems to constantly monitor environmental changes and accordingly adjust growth, differentiation, and cellular stress programs. The evolutionarily conserved, nutrient-responsive, mechanistic ... -
Genome-wide screens in yeast models towards understanding chronological lifespan regulation.
Legon, L; Rallis, C (Oxford University Press, 2021-03-17)Cellular models such as yeasts are a driving force in biogerontology studies. Their simpler genome, short lifespans and vast genetic and genomics resources make them ideal to characterise pro-ageing and anti-ageing genes ... -
Increased fidelity of protein synthesis extends lifespan.
Martinez-Miguel, VE; Lujan, C; Espie-Caullet, T; Martinez-Martinez, D; Moore, S; Backes, C; Gonzalez, S; Galimov, ER; Brown, AEX; Halic, M (Cell Press, 2021-09-14)Loss of proteostasis is a fundamental process driving aging. Proteostasis is affected by the accuracy of translation, yet the physiological consequence of having fewer protein synthesis errors during multi-cellular organismal ... -
Interplays of AMPK and TOR in Autophagy Regulation in Yeast.
Alao, J-P; Legon, L; Dabrowska, A; Tricolici, A-M; Kumar, J; Rallis, C (MDPI, 2023-02-04)Cells survey their environment and need to balance growth and anabolism with stress programmes and catabolism towards maximum cellular bioenergetics economy and survival. Nutrient-responsive pathways, such as the mechanistic ... -
The longevity and reversibility of quiescence in Schizosaccharomyces pombe are dependent upon the HIRA histone chaperone
Gal, C; Cochrane, GA; Morgan, BA; Rallis, C; Bahler, J; Whitehall, SK (Taylor and Francis Group, 2023-08-27)Quiescence (G0) is a reversible non-dividing state that facilitates cellular survival in adverse conditions. Here, we demonstrate that the HIRA histone chaperone complex is required for the reversibility and longevity of ... -
Nutrient-Response Pathways in Healthspan and Lifespan Regulation.
Dabrowska, A; Kumar, J; Rallis, C (MDPI, 2022-05-06)Cellular, small invertebrate and vertebrate models are a driving force in biogerontology studies. Using various models, such as yeasts, appropriate tissue culture cells, Drosophila, the nematode Caenorhabditis elegans and ... -
Ribosomal Biogenesis and Heterogeneity in Development, Disease, and Aging
Islam, RA; Rallis, C (2023)