Browsing Awaiting Allocation by Author "Garraway, LA"
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Stepwise-edited, human melanoma models reveal mutations' effect on tumor and microenvironment.
Hodis, E; Torlai Triglia, E; Kwon, JYH; Biancalani, T; Zakka, LR; Parkar, S; Hütter, J-C; Buffoni, L; Delorey, TM; Phillips, D (2022-04-29)Establishing causal relationships between genetic alterations of human cancers and specific phenotypes of malignancy remains a challenge. We sequentially introduced mutations into healthy human melanocytes in up to five ...