Browsing Awaiting Allocation by Author "Fernandes, C"
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Distinct, dosage-sensitive requirements for the autism-associated factor CHD8 during cortical development.
Hurley, S; Mohan, C; Suetterlin, P; Ellingford, R; Riegman, KLH; Ellegood, J; Caruso, A; Michetti, C; Brock, O; Evans, R (2021-02-24)BACKGROUND: CHD8 haploinsufficiency causes autism and macrocephaly with high penetrance in the human population. Chd8 heterozygous mice exhibit relatively subtle brain overgrowth and little gene expression changes in the ...