Browsing Awaiting Allocation by Author "Backes, C"
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Increased fidelity of protein synthesis extends lifespan.
Martinez-Miguel, VE; Lujan, C; Espie-Caullet, T; Martinez-Martinez, D; Moore, S; Backes, C; Gonzalez, S; Galimov, ER; Brown, AEX; Halic, M (Cell Press, 2021-09-14)Loss of proteostasis is a fundamental process driving aging. Proteostasis is affected by the accuracy of translation, yet the physiological consequence of having fewer protein synthesis errors during multi-cellular organismal ...