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Now showing items 217-234 of 234
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Topoisomerase I poison-triggered immune gene activation is markedly reduced in human small-cell lung cancers by impairment of the cGAS/STING pathway.
(Cell Press, 2022-10-07)BACKGROUND: Current immunotherapy strategies have contrasting clinical results in human lung cancer patients as small-cell lung cancers (SCLC) often show features of immunological cold tumours. Topoisomerase 1 (TOP1) poisons ... -
Transcriptomic responses to location learning by honeybee dancers are partly mirrored in the brains of dance-followers.
(The Royal Society, 2023-12-20)The waggle dances of honeybees are a strikingly complex form of animal communication that underlie the collective foraging behaviour of colonies. The mechanisms by which bees assess the locations of forage sites that they ... -
Transparency Measures in Procurement for Sustainable Social Supply Chain
(IGI Global, 2024-05-22)An organisation's long-term success is not only based on its bottom line but also its contribution to the people and the planet's future. Social concerns in the supply chain have been gaining prominence that has encouraged ... -
Traumatic Brain Injuries: A Cross-Sectional Study of Traumatic Brain Injuries at a Tertiary Care Trauma Center in the Punjab, Pakistan
(Cambridge University Press (CUP), 2023)<jats:title>Abstract</jats:title> <jats:sec id="S193578932100361X_as1"> <jats:title>Introduction:</jats:title> <jats:p>Traumatic brain injuries (TBIs) are 1 of the most common reasons for young adult death and disability. ... -
Treatment de-escalation for stage II seminoma
(Nature Research, 2023-03-07) -
Tropical Combinatorics
(American Mathematical Society (AMS), 2023-01-01) -
Tryptophan to Tryptophan Hole Hopping in an Azurin Construct.
(2024-01-11)Electron transfer (ET) between neutral and cationic tryptophan residues in the azurin construct [ReI(H126)(CO)3(dmp)](W124)(W122)CuI (dmp = 4,7-Me2-1,10-phenanthroline) was investigated by Born-Oppenheimer quantum-mechan ... -
Two-Photon Absorption: An Open Door to the NIR-II Biological Window?
(2022)The way in which photons travel through biological tissues and subsequently become scattered or absorbed is a key limitation for traditional optical medical imaging techniques using visible light. In contrast, near-infrared ... -
Understanding the complex dynamics of zebra mussel invasions over several decades in European rivers: drivers, impacts and predictions
The zebra mussel Dreissena polymorpha is one of the most successful, notorious, and detrimental aquatic invasive non-native species worldwide, having invaded Europe and North America while causing substantial ecological ... -
USP7 inactivation suppresses APC-mutant intestinal hyperproliferation and tumor development
(Cell Press, 2023-01-19)Adenomatous polyposis coli (APC) mutation is the hallmark of colorectal cancer (CRC), resulting in constitutive WNT activation. Despite decades of research, targeting WNT signaling in cancer remains challenging due to its ... -
White generosity: black freedom faced with good intentions
(Emerald, 2020-09-22)I advance a theory of white generosity, a product of whiteness and of hierarchized relationships between races characterised by the giving to the racialized person that which has not been asked for and which has no practical ...