Browsing Cell and Molecular Biology by Subject "Animals"
Now showing items 1-16 of 16
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Astroglial Plasticity Is Implicated in Hippocampal Remodelling in Adult Rats Exposed to Antenatal Dexamethasone.
(2015)The long-term effects of antenatal dexamethasone treatment on brain remodelling in 3-month-old male Sprague Dawley rats whose mothers had been treated with dexamethasone were investigated in the present study. Dorsal ... -
Benznidazole-resistance in Trypanosoma cruzi is a readily acquired trait that can arise independently in a single population.
(2012-07-15)Benznidazole is the frontline drug used against Trypanosoma cruzi, the causative agent of Chagas disease. However, treatment failures are often reported. Here, we demonstrate that independently acquired mutations in the ... -
Cortical overexpression of neuronal calcium sensor-1 induces functional plasticity in spinal cord following unilateral pyramidal tract injury in rat.
(2010-06-22)Following trauma of the adult brain or spinal cord the injured axons of central neurons fail to regenerate or if intact display only limited anatomical plasticity through sprouting. Adult cortical neurons forming the ... -
Demographic History of the Human Commensal Drosophila melanogaster.
(2019-03-01)The cohabitation of Drosophila melanogaster with humans is nearly ubiquitous. Though it has been well established that this fly species originated in sub-Saharan Africa, and only recently has spread globally, many details ... -
Estimating the distribution of selection coefficients from phylogenetic data using sitewise mutation-selection models.
(2012-03)Estimation of the distribution of selection coefficients of mutations is a long-standing issue in molecular evolution. In addition to population-based methods, the distribution can be estimated from DNA sequence data by ... -
Evidence for the fixation of gene duplications by positive selection in Drosophila.
(2016-06)Gene duplications play a key role in the emergence of novel traits and in adaptation. But despite their centrality to evolutionary processes, it is still largely unknown how new gene duplicates are initially fixed within ... -
Neither phylogenomic nor palaeontological data support a Palaeogene origin of placental mammals.
(2014-01)O'Leary et al. (O'Leary et al. 2013 Science 339, 662-667. (doi:10.1126/science.1229237)) performed a fossil-only dating analysis of mammals, concluding that the ancestor of placentals post-dated the Cretaceous-Palaeogene ... -
Nitrotriazole-based acetamides and propanamides with broad spectrum antitrypanosomal activity.
(2016-11-10)3-Nitro-1H-1,2,4-triazole-based acetamides bearing a biphenyl- or a phenoxyphenyl moiety have shown remarkable antichagasic activity both in vitro and in an acute murine model, as well as substantial in vitro antileishmanial ... -
Olfactory receptor pseudo-pseudogenes
(Springer Nature, 2016-11-03) -
Proteomic identification of heterogeneous nuclear ribonucleoprotein L as a novel component of SLM/Sam68 Nuclear Bodies.
(2009-11-13)BACKGROUND: Active pre-mRNA splicing occurs co-transcriptionally, and takes place throughout the nucleoplasm of eukaryotic cells. Splicing decisions are controlled by networks of nuclear RNA-binding proteins and their ... -
Skeletal muscle repair by adult human mesenchymal stem cells from synovial membrane.
(2003-03-17)We have demonstrated previously that adult human synovial membrane-derived mesenchymal stem cells (hSM-MSCs) have myogenic potential in vitro (De Bari, C., F. Dell'Accio, P. Tylzanowski, and F.P. Luyten. 2001. Arthritis ... -
Survey of Global Genetic Diversity Within the Drosophila Immune System
(Oxford University Press (OUP), 2017-01-01) -
Targeted molecular profiling of rare olfactory sensory neurons identifies fate, wiring, and functional determinants
(eLife Sciences Publications, 2021-03-05)Determining the molecular properties of neurons is essential to understand their development, function and evolution. Using Targeted DamID (TaDa), we characterize RNA polymerase II occupancy and chromatin accessibility in ...