Browsing Cell and Molecular Biology by Author "Pryce, G"
Now showing items 1-4 of 4
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Big conductance calcium-activated potassium channel openers control spasticity without sedation
Baker, D; Pryce, G; Visintin, C; Sisay, S; Bondarenko, AI; Ho, WSV; Jackson, SJ; Williams, TE; Al-Izki, S; Sevastou, I (2017-08) -
Big conductance calcium-activated potassium channel openers control spasticity without sedation.
Baker, D; Pryce, G; Visintin, C; Sisay, S; Bondarenko, AI; Vanessa Ho, WS; Jackson, SJ; Williams, TE; Al-Izki, S; Sevastou, I (John Wiley and Sons, 2017-07-07)BACKGROUND AND PURPOSE: Our initial aim was to generate cannabinoid agents that control spasticity, occurring as a consequence of multiple sclerosis (MS), whilst avoiding the sedative side effects associated with cannabis. ... -
Depletion of CD20 B cells fails to inhibit relapsing mouse experimental autoimmune encephalomyelitis
Sefia, E; Pryce, G; Meier, U-C; Giovannoni, G; Baker, D (2017-05) -
Evaluation of the Effects of Sativex (THC BDS: CBD BDS) on Inhibition of Spasticity in a Chronic Relapsing Experimental Allergic Autoimmune Encephalomyelitis: A Model of Multiple Sclerosis.
Hilliard, A; Stott, C; Wright, S; Guy, G; Pryce, G; Al-Izki, S; Bolton, C; Giovannoni, G (2012)This study investigated the antispasticity potential of Sativex in mice. Chronic relapsing experimental allergic encephalomyelitis was induced in adult ABH mice resulting in hind limb spasticity development. Vehicle, ...