Browsing Cell and Molecular Biology by Author "Leigh, IM"
Now showing items 1-3 of 3
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Overexpression of the Axl tyrosine kinase receptor in cutaneous SCC-derived cell lines and tumours
Green, J; Ikram, M; Vyas, J; Patel, N; Proby, CM; Ghali, L; Leigh, IM; O'Toole, EA; Storey, A (2006-05-22) -
Reduced SMAD2/3 activation independently predicts increased depth of human cutaneous squamous cell carcinoma.
Rose, AM; Spender, LC; Stephen, C; Mitchell, A; Rickaby, W; Bray, S; Evans, AT; Dayal, J; Purdie, KJ; Harwood, CA (2018-03-06)The incidence of cutaneous squamous cell carcinoma (cSCC) is rising. Whilst the majority are cured surgically, aggressive metastatic cSCC carry a poor prognosis. Inactivating mutations in transforming growth factor beta ... -
The Role of Human Papillomaviruses and Polyomaviruses in BRAF-Inhibitor Induced Cutaneous Squamous Cell Carcinoma and Benign Squamoproliferative Lesions.
Purdie, KJ; Proby, CM; Rizvi, H; Griffin, H; Doorbar, J; Sommerlad, M; Feltkamp, MC; der Meijden, EV; Inman, GJ; South, AP (2018)Background: Human papillomavirus (HPV) has long been proposed as a cofactor in the pathogenesis of cutaneous squamous cell carcinoma (cSCC). More recently, the striking clinico-pathological features of cSCCs that complicate ...