Browsing Cell and Molecular Biology by Author "Kaiser, M"
Now showing items 1-5 of 5
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3-Nitrotriazole-based piperazides as potent antitrypanosomal agents
Papadopoulou, MV; Bloomer, WD; Rosenzweig, HS; O'Shea, IP; Wilkinson, SR; Kaiser, M (2015-10) -
Antitrypanosomal activity of 5-nitro-2-aminothiazole-based compounds
Papadopoulou, MV; Bloomer, WD; Rosenzweig, HS; WILKINSON, SR; Szular, J; Kaiser, M (Elsevier, 2016-07-19)A small series of 5-nitro-2-aminothiazole-based amides containing arylpiperazine-, biphenyl- or aryloxyphenyl groups in their core were synthesized and evaluated as anti-trypanosomatid agents. All tested compounds were ... -
Discovery of potent nitrotriazole-based antitrypanosomal agents: In vitro and in vivo evaluation
Papadopoulou, MV; Bloomer, WD; Rosenzweig, HS; O’Shea, IP; Wilkinson, SR; Kaiser, M; Chatelain, E; Ioset, J-R (2015-10) -
Nitrotriazole-based acetamides and propanamides with broad spectrum antitrypanosomal activity.
Papadopoulou, MV; Bloomer, WD; Rosenzweig, HS; Wilkinson, SR; Szular, J; Kaiser, M (2016-11-10)3-Nitro-1H-1,2,4-triazole-based acetamides bearing a biphenyl- or a phenoxyphenyl moiety have shown remarkable antichagasic activity both in vitro and in an acute murine model, as well as substantial in vitro antileishmanial ... -
Novel 3-nitrotriazole-based amides and carbinols as bifunctional anti-Chagasic agents.
Papadopoulou, MV; Bloomer, WD; Lepesheva, GI; Rosenzweig, HS; Kaiser, M; Aguilera-Venegas, B; WILKINSON, SR; Chatelain, E; Ioset, JR (American Chemical Society, 2015-01-23)3-Nitro-1H-1,2,4-triazole-based amides with a linear, rigid core and 3-nitrotriazole-based fluconazole analogs were synthesized as dual functioning antitrypanosomal agents. Such compounds are excellent substrates for type ...