Browsing School of Biological and Chemical Sciences by Subject "Saccharomyces cerevisiae Proteins"
Now showing items 1-3 of 3
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Eic1 links Mis18 with the CCAN/Mis6/Ctf19 complex to promote CENP-A assembly.
(2014-04-30)CENP-A chromatin forms the foundation for kinetochore assembly. Replication-independent incorporation of CENP-A at centromeres depends on its chaperone HJURP(Scm3), and Mis18 in vertebrates and fission yeast. The recruitment ... -
Misregulation of cell cycle-dependent methylation of budding yeast CENP-A contributes to chromosomal instability.
(2023-09-01)Centromere (CEN) identity is specified epigenetically by specialized nucleosomes containing evolutionarily conserved CEN-specific histone H3 variant CENP-A (Cse4 in Saccharomyces cerevisiae, CENP-A in humans), which is ... -
A sphingolipid-dependent diffusion barrier confines ER stress to the yeast mother cell.
(2014-05-06)In many cell types, lateral diffusion barriers compartmentalize the plasma membrane and, at least in budding yeast, the endoplasmic reticulum (ER). However, the molecular nature of these barriers, their mode of action and ...