Browsing School of Biological and Chemical Sciences by Subject "Saccharomyces cerevisiae"
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Estimating translational selection in eukaryotic genomes.
(2009-02)Natural selection on codon usage is a pervasive force that acts on a large variety of prokaryotic and eukaryotic genomes. Despite this, obtaining reliable estimates of selection on codon usage has proved complicated, perhaps ... -
Misregulation of cell cycle-dependent methylation of budding yeast CENP-A contributes to chromosomal instability.
(2023-09-01)Centromere (CEN) identity is specified epigenetically by specialized nucleosomes containing evolutionarily conserved CEN-specific histone H3 variant CENP-A (Cse4 in Saccharomyces cerevisiae, CENP-A in humans), which is ... -
A sphingolipid-dependent diffusion barrier confines ER stress to the yeast mother cell.
(2014-05-06)In many cell types, lateral diffusion barriers compartmentalize the plasma membrane and, at least in budding yeast, the endoplasmic reticulum (ER). However, the molecular nature of these barriers, their mode of action and ...