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dc.contributor.authorGrimes, CAen_US
dc.contributor.authorBolhuis, DPen_US
dc.contributor.authorHe, FJen_US
dc.contributor.authorNowson, CAen_US
dc.date.accessioned2017-09-01T16:18:28Z
dc.date.available2015-12-21en_US
dc.date.issued2016-01-18en_US
dc.date.submitted2017-07-13T07:26:55.194Z
dc.identifier.urihttp://qmro.qmul.ac.uk/xmlui/handle/123456789/25588
dc.description.abstractBACKGROUND: Overweight and obesity in children and adults is a major public health concern. Emerging evidence suggests dietary sodium intake may be associated with obesity. This systematic review and meta-analysis will aim to (i) assess the relation between dietary sodium intake and measures of adiposity in children and adults and (ii) examine the relation between sodium intake and sugar-sweetened beverage (SSB) consumption, which is a known risk factor for obesity. METHODS/DESIGN: An electronic search will be conducted using Medline Complete, CINAHL, Scopus, Embase and Cochrane central register of controlled trials (CENTRAL). The search strategy will identify published peer-reviewed articles that report on dietary sodium and either a marker of adiposity or SSB consumption. Only human studies (ages >1 year) in English will be included, and no limits will be placed on publication date. No restrictions will be placed on the method of sodium intake assessment. Cross-sectional, prospective studies, and randomised controlled trials with a duration of ≥ 3 months will be included. Studies with participants with renal disease, cancer, type 1 diabetes or heart failure or who are pregnant will be excluded. To assess the quality of studies, the Cochrane's Collaboration tool for assessing risk of bias in randomised trials will be used for randomised controlled trials (RCTs), and the modified Newcastle-Ottawa Scale will be used for cross-sectional and prospective studies. Meta-analysis will be used to assess the relation of sodium intake with two primary outcomes: (i) BMI and body weight in adults and BMI z-score in children and (ii) weight category (i.e. healthy weight vs. overweight/obese). For any outcomes in which meta-analysis is not possible, we will present data as a systematic review. Findings will be grouped and reported separately for children and adolescents (ages 1-17 years) and adults (ages >18 years). DISCUSSION: This review and meta-analysis will provide insight into the relation between dietary sodium intake and overweight and obesity. This information can be used to inform public health policies which target population sodium consumption. SYSTEMATIC REVIEW REGISTRATION: Prospero CRD42015016440.en_US
dc.description.sponsorshipCG is supported by a National Heart Foundation of Australia Postdoctoral Fellowship (Award ID: 100155).en_US
dc.format.extent7 - ?en_US
dc.languageengen_US
dc.language.isoenen_US
dc.relation.ispartofSyst Reven_US
dc.rightsThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
dc.subjectAdulten_US
dc.subjectChilden_US
dc.subjectHumansen_US
dc.subjectObesityen_US
dc.subjectOverweighten_US
dc.subjectSodium, Dietaryen_US
dc.subjectSystematic Reviews as Topicen_US
dc.titleDietary sodium intake and overweight and obesity in children and adults: a protocol for a systematic review and meta-analysis.en_US
dc.typeArticle
dc.rights.holder© Grimes et al. 2016.
dc.identifier.doi10.1186/s13643-015-0175-3en_US
pubs.author-urlhttps://www.ncbi.nlm.nih.gov/pubmed/26781844en_US
pubs.notesNot knownen_US
pubs.organisational-group/Queen Mary University of London
pubs.organisational-group/Queen Mary University of London/Faculty of Medicine & Dentistry
pubs.organisational-group/Queen Mary University of London/Faculty of Medicine & Dentistry/Wolfson Institute of Preventive Medicine
pubs.organisational-group/Queen Mary University of London/Faculty of Medicine & Dentistry/Wolfson Institute of Preventive Medicine/Environmental & Preventive Medicine
pubs.organisational-group/Queen Mary University of London/REF
pubs.organisational-group/Queen Mary University of London/REF/REF - UoA 01
pubs.publication-statusPublished onlineen_US
pubs.volume5en_US
dcterms.dateAccepted2015-12-21en_US


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