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CRISPR/Cas9-Mediated Trp53 and Brca2 Knockout to Generate Improved Murine Models of Ovarian High-Grade Serous Carcinoma

dc.contributor.authorWalton, Jen_US
dc.contributor.authorBlagih, Jen_US
dc.contributor.authorEnnis, Den_US
dc.contributor.authorLeung, Een_US
dc.contributor.authorDowson, Sen_US
dc.contributor.authorFarquharson, Men_US
dc.contributor.authorTookman, LAen_US
dc.contributor.authorOrange, Cen_US
dc.contributor.authorAthineos, Den_US
dc.contributor.authorMason, Sen_US
dc.contributor.authorStevenson, Den_US
dc.contributor.authorBlyth, Ken_US
dc.contributor.authorStrathdee, Den_US
dc.contributor.authorBalkwill, FRen_US
dc.contributor.authorVousden, Ken_US
dc.contributor.authorLockley, Men_US
dc.contributor.authorMcNeish, IAen_US
dc.date.accessioned2017-08-09T11:11:21Z
dc.date.available2016-08-02en_US
dc.date.issued2016-10en_US
dc.date.submitted2016-11-23T09:10:58.090Z
dc.identifier.issn0008-5472en_US
dc.identifier.urihttp://qmro.qmul.ac.uk/xmlui/handle/123456789/25148
dc.description.sponsorshipThis work was funded by the University of Glasgow and Cancer Research UK [grants C16420/A12995 (I.A. McNeish), C596/A18076 (K. Vousden), C608/A15973 (I.A. McNeish), C596/A20921 (K. Vousden), and C16420/A16354 (F.R. Balkwill)]. All animal work was performed in the Biological Services Unit facilities at the Cancer Research UK Beatson Institute (Cancer Research UK grant C596/A17196).en_US
dc.format.extent6118 - 6129en_US
dc.relation.ispartofCANCER RESEARCHen_US
dc.titleCRISPR/Cas9-Mediated Trp53 and Brca2 Knockout to Generate Improved Murine Models of Ovarian High-Grade Serous Carcinomaen_US
dc.typeArticle
dc.rights.holder© 2016 American Association for Cancer Research.
dc.identifier.doi10.1158/0008-5472.CAN-16-1272en_US
pubs.author-urlhttp://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000385627600022&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=612ae0d773dcbdba3046f6df545e9f6aen_US
pubs.issue20en_US
pubs.notesNot knownen_US
pubs.publication-statusPublisheden_US
pubs.volume76en_US
qmul.funderNew treatments for chemotherapy resistant high grader serous ovarian cancer::CRUKen_US


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