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dc.contributor.authorHurley, MVen_US
dc.contributor.authorWalsh, NEen_US
dc.contributor.authorMitchell, HLen_US
dc.contributor.authorPimm, TJen_US
dc.contributor.authorWilliamson, Een_US
dc.contributor.authorJones, RHen_US
dc.contributor.authorReeves, BCen_US
dc.contributor.authorDieppe, PAen_US
dc.contributor.authorPatel, Aen_US
dc.description.abstractOBJECTIVE: To conduct an economic evaluation of the Enabling Self-Management and Coping with Arthritic Knee Pain through Exercise (ESCAPE-knee pain) program. METHODS: Alongside a clinical trial, we estimated the costs of usual primary care and participation in ESCAPE-knee pain delivered to individuals (Indiv-rehab) or groups of 8 participants (Grp-rehab). Information on resource use and informal care received was collected during face-to-face interviews. Cost-effectiveness and cost-utility were assessed from between-group differences in costs, function (primary clinical outcome), and quality-adjusted life years (QALYs). Cost-effectiveness acceptability curves were constructed to represent uncertainty around cost-effectiveness. RESULTS: Rehabilitation (regardless of whether Indiv-rehab or Grp-rehab) cost 224 pounds (95% confidence interval [95% CI] 184 pounds, 262 pounds) more per person than usual primary care. The probability of rehabilitation being more cost-effective than usual primary care was 90% if decision makers were willing to pay 1,900 pounds for improvements in functioning. Indiv-rehab cost 314 pounds/person and Grp-rehab 125 pounds/person. Indiv-rehab cost 189 pounds (95% CI 168 pounds, 208 pounds) more per person than Grp-rehab. The probability of Indiv-rehab being more cost-effective than Grp-rehab increased as willingness to pay (WTP) increased, reaching 50% probability at WTP 5,500 pounds. The lack of differences in QALYs across the arms led to lower probabilities of cost-effectiveness based on this outcome. CONCLUSION: Provision of ESCAPE-knee pain had small cost implications, but it was more likely to be cost-effective in improving function than usual primary care. Group rehabilitation reduces costs without compromising clinical effectiveness, increasing probability of cost-effectiveness.en_US
dc.format.extent1220 - 1229en_US
dc.relation.ispartofArthritis Rheumen_US
dc.subjectAdaptation, Psychologicalen_US
dc.subjectAged, 80 and overen_US
dc.subjectChronic Diseaseen_US
dc.subjectCost-Benefit Analysisen_US
dc.subjectCosts and Cost Analysisen_US
dc.subjectExercise Therapyen_US
dc.subjectMiddle Ageden_US
dc.subjectOsteoarthritis, Kneeen_US
dc.subjectPrimary Health Careen_US
dc.subjectQuality-Adjusted Life Yearsen_US
dc.subjectSelf Careen_US
dc.subjectUnited Kingdomen_US
dc.titleEconomic evaluation of a rehabilitation program integrating exercise, self-management, and active coping strategies for chronic knee pain.en_US
pubs.notesNot knownen_US

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