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Brief Report: Isogenic Induced Pluripotent Stem Cell Lines From an Adult With Mosaic Down Syndrome Model Accelerated Neuronal Ageing and Neurodegeneration

dc.contributor.authorMurray, Aen_US
dc.contributor.authorLetourneau, Aen_US
dc.contributor.authorCanzonetta, Cen_US
dc.contributor.authorStathaki, Een_US
dc.contributor.authorGimelli, Sen_US
dc.contributor.authorSloan-Bena, Fen_US
dc.contributor.authorAbrehart, Ren_US
dc.contributor.authorGoh, Pen_US
dc.contributor.authorLim, Sen_US
dc.contributor.authorBaldo, Cen_US
dc.contributor.authorDagna-Bricarelli, Fen_US
dc.contributor.authorHannan, Sen_US
dc.contributor.authorMortensen, Men_US
dc.contributor.authorBallard, Den_US
dc.contributor.authorCourt, DSen_US
dc.contributor.authorFusaki, Nen_US
dc.contributor.authorHasegawa, Men_US
dc.contributor.authorSmart, TGen_US
dc.contributor.authorBishop, Cen_US
dc.contributor.authorAntonarakis, SEen_US
dc.contributor.authorGroet, Jen_US
dc.contributor.authorNizetic, Den_US
dc.date.accessioned2016-10-07T11:16:40Z
dc.date.available2015-01-17en_US
dc.date.issued2015-06en_US
dc.date.submitted2016-08-17T10:03:21.778Z
dc.identifier.issn1066-5099en_US
dc.identifier.other10.1002/stem.1968
dc.identifier.urihttp://qmro.qmul.ac.uk/xmlui/handle/123456789/15766
dc.description.sponsorshipThis work was supported by the project grants from the KayKendall Leukaemia Fund (KKL632), and Fondation JeromeLejeune (2011B/960), by The Wellcome Trust “LonDownS Con-sortium” Strategic Funding Award (098330/Z/12/Z), and theLee Kong Chian School of Medicine, Nanyang TechnologicalUniversity-Singapore start-up funding grant M4230024 toD.N., by the “AnEUploidy Consorium” grant from FrameworkProgramme 6 from the EU Commission to D.N. and S.E.A., aswell as SNF 144082 and ERC 249968 grants to S.E.A. We alsothank Barts and The London Charity and the grant 520/1489:“Development of a National Centre for Bowel Research andSurgical Innovation (NCBRSI)” for purchase of high contentimaging equipment.en_US
dc.format.extent2077 - 2084en_US
dc.language.isoenen_US
dc.relation.ispartofSTEM CELLSen_US
dc.rightsCreative Commons Attribution License
dc.subjectDown syndromeen_US
dc.subjectNeurodegenerationen_US
dc.subjectNeurogenesisen_US
dc.subjectNeuronal differentiationen_US
dc.titleBrief Report: Isogenic Induced Pluripotent Stem Cell Lines From an Adult With Mosaic Down Syndrome Model Accelerated Neuronal Ageing and Neurodegenerationen_US
dc.typeArticle
dc.rights.holder2015. The authors
dc.identifier.doi10.1002/stem.1968en_US
pubs.author-urlhttp://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000354882500033&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=612ae0d773dcbdba3046f6df545e9f6aen_US
pubs.issue6en_US
pubs.notesNo embargoen_US
pubs.publication-statusPublisheden_US
pubs.volume33en_US


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