Now showing items 1-2 of 2

    • Bioorthogonal Swarming: In Situ Generation of Dendrimers 

      Zhang, Y; Ucuncu, M; Gambardella, A; Baibek, A; Geng, J; Zhang, S; Clavadetscher, J; Litzen, I; Bradley, M; Lilienkampf, A (American Chemical Society, 2020-12-16)
      With the aid of bioorthogonal chemistry, we demonstrate the fabrication of synthetic dendrimers in situ around living cells. Using tetrazine dienophile and aminooxyl/hydrazide aldehyde chemistries, the density of functional ...
    • Dyeing fungi: amphotericin B based fluorescent probes for multiplexed imaging. 

      Baibek, A; Üçüncü, M; Short, B; Ramage, G; Lilienkampf, A; Bradley, M (2021-02-23)
      The clinically used antifungal polyene amphotericin B was conjugated, via the mycosamine and the aglycon moieties, to fluorophores. The Cy5 conjugated probe showed selective labelling of fungi in the presence of bacteria, ...