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Now showing items 8741-8760 of 40629
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Development of a Speech Quality Database Under Uncontrolled Conditions
(2020-10-25)Objective audio quality assessment is preferred to avoid time-consuming and costly listening tests. The development of objective quality metrics depends on the availability of datasets appropriate to the application under ... -
Development of a standardised set of outcome measures for use in routine orthodontic clinical trials
(Queen Mary University of London, 2020)Aims: To develop an agreed, standardised set of outcome measures for use in clinical trials of routine orthodontic treatment for non-cleft/orthognathic patients. Methods: A mixed-methods approach was used. In stage I, ... -
The development of a theory and evidence-based intervention to aid implementation of exercise into the prostate cancer care pathway with a focus on healthcare professional behaviour, the STAMINA trial.
(BioMed Central, 2021-03-25)BACKGROUND: Twice-weekly supervised aerobic and resistance exercise for 12 weeks reduces fatigue and improves quality of life in men on Androgen Deprivation Therapy for prostate cancer. Despite the National Institute for ... -
Development of a WNT-selective oncolytic adenovirus for imaging the therapy of colorectal cancers.
(2008)Introduction: The concept of oncolytic adenoviruses has been validated in preclinical studies but clinical trials have demonstrated that the virus spread remains limited and the virus fails to infect all cancer cells in ... -
Development of action representation during adolescence
(Elsevier/Science Direct, 2007)During adolescence the body undergoes many physical changes. These changes necessitate an updating of internal models of action. Here, we tested the hypothesis that internal models undergo refinement between adolescence ... -
Development of an 90Y calibration source and rejection of pileup backgrounds in the SNO+ experiment
(Queen Mary University of London, 19/12/2018)SNO+ is a multi-purpose liquid scintillator detector with the main aim of investigating neutrinoless double beta decay (0 2 ) of 130Te. The sensitivity of such rare decay searches is limited by backgrounds, therefore it ... -
Development of an artificial intelligence system to identify hypoglycaemia via ECG in adults with type 1 diabetes: protocol for data collection under controlled and free-living conditions.
(BMJ Publishing Group Ltd, 2023-04-18)INTRODUCTION: Hypoglycaemia is a harmful potential complication in people with type 1 diabetes mellitus (T1DM) and can be exacerbated in patients receiving treatment, such as insulin therapies, by the very interventions ... -
The Development of an Automated, Fluorescent, Quantitative Three-Dimensional In Vitro Organotypic Invasion Assay
(Queen Mary University of London, 2017-11-27)Tumour metastasis is a complex multi-step biological process, which involves dispersion of cancer cells to various organ sites within the body. The tumour-stroma interface plays an important role within cancer progression ... -
Development of an immunocompetent model of oncolytic adenoviral gene therapy for ovarian cancer.
(Queen Mary University of London, 2012)Oncolytic adenoviral gene therapy has potential as a novel anti-cancer agent for ovarian cancer. Host immune responses are thought to contribute to its therapeutic effects. However further evaluation has been hampered by ... -
The Development of an in vitro 3D Histotypic Model of The Human Eccrine Sweat Gland.
(Queen Mary University of London, 2016-05-05)The human eccrine sweat gland is present on most body sites and is crucial for thermoregulation. Yet, little is known on the mechanisms that govern its function and its morphogenesis. The main reason for the lack in ... -
Development of an in vitro microfluidic model to study the role of microenvironmental cells in oral cancer metastasis
(Taylor and Francis, 2023-04-25) -
Development of an in vitro microfluidic model to study the role of microenvironmental cells in oral cancer metastasis.
(2023)Metastasis occurs when cancer cells leave the primary tumour and travel to a secondary site to form a new lesion. The tumour microenvironment (TME) is recognised to greatly influence this process, with for instance the ...