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Now showing items 7828-7847 of 42064
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Crystal structures of the CPAP/STIL complex reveal its role in centriole assembly and human microcephaly.
(2013-09-17)Centrioles organise centrosomes and template cilia and flagella. Several centriole and centrosome proteins have been linked to microcephaly (MCPH), a neuro-developmental disease associated with small brain size. CPAP (MCPH6) ... -
Crystal structures of the human IgD Fab reveal insights into CH1 domain diversity
(Elsevier, 2023-06-01)Antibodies of the IgD isotype remain the least well characterized of the mammalian immunoglobulin isotypes. Here we report three-dimensional structures for the Fab region of IgD, based on four different crystal structures, ... -
Crystallization of trans 1, 4 polyisoprene morphology and kinetics.
(Queen Mary University of London, 1973)A detailed electron microscopic study of the morphology and kinetics of crystallization of trans-1,4-polyisoprene with cis isoprene units varying from Of to 19.8 has been carried out. Two crystal structures of trans3., ... -
Crystallographic and Microstructural Studies of Dental Enamel using Synchrotron X-ray Diffraction and Complementary Techniques.
(Queen Mary University of London, 2014)The complex microstructure and properties of dental enamel have been studied for decades using a variety of quantitative and qualitative techniques in order to gain a greater depth of understanding behind the chemical and ... -
The crystallographic structure of dental enamel and related apatites
(Queen Mary University of London, 1964)Synthetic, biological and mineralogical carbonate-containing apatites have been studied, principally by infra-red absorption spectroscopy (using polarised or unpolarised radiation), The substitution of a carbonate ion ... -
Crystals, regularisation and the Mullineux map
(EMS Press, 2021)The Mullineux map is a combinatorial function on partitions which describes the effect of tensoring a simple module for the symmetric group in characteristic $p$ with the one-dimensional sign representation. It can also ... -
CSF neurofilament light chain profiling and quantitation in neurological diseases.
(Oxford University Press, 2024)Neurofilament light chain is an established marker of neuroaxonal injury that is elevated in CSF and blood across various neurological diseases. It is increasingly used in clinical practice to aid diagnosis and monitor ... -
CSF neurofilament light chain reflects corticospinal tract degeneration in ALS
(Wiley Open Access, 2015-05-25)Objective: Diffusion tensor imaging (DTI) is sensitive to white matter tract pathology. A core signature involving the corticospinal tracts (CSTs) has been identified in amyotrophic lateral sclerosis (ALS). Raised ... -
CSF neurofilament light chain testing as an aid to determine treatment strategies in MS
(Lippincott, Williams & Wilkins, 2020-11)Objective: To evaluate the use of CSF neurofilament light chain (NfL) measurements in clinical practice as well as their effect on treatment strategies and outcomes in multiple sclerosis (MS) patients. Methods: This was ... -
CSF neurofilament light chain testing as an aid to determine treatment strategies in MS.
(2020-11)OBJECTIVE: To evaluate the use of CSF neurofilament light chain (NfL) measurements in clinical practice as well as their effect on treatment strategies and outcomes in patients with MS. METHODS: This was an observational ... -
CSN1 Somatic Mutations in Penile Squamous Cell Carcinoma
(American Association for Cancer Research, 2016-06-20)Other than an association with HPV infection, little is known about the genetic alterations determining the development of penile cancer. Although penile cancer is rare in the developed world, it presents a significant ...
