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Now showing items 33020-33039 of 41346
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The Role of Patient Preferences in the Arts Therapies
Background Consideration of patient preferences is in line with recovery and resource-oriented approaches to mental health treatment and is recommended by national and international guidelines. However, the implications ... -
Role of peroxisome proliferator-activated receptor-β/δ in acute myocardial infarction, septic shock and sepsis
(2011)Peroxisome Proliferator-Activated Receptors (PPARs) are ligand activated transcription factors that belong to the nuclear hormone receptor family. In this thesis, I have investigated the anti-inflammatory role of PPAR-β/δ ... -
The Role of Personal Values and Empathy in a Cooperative Game
Are the personal values of others a relevant cue when thinking about cooperating, and do values matter more than empathizing with others? To address these questions, the present study presented participants (N = 120) with ... -
ROLE OF PHYSIOCHEMICAL PARAMETERS IN THE OSTEOGENIC POTENTIAL OF CALCIUM PHOSPHATE BIOMATERIALS
(Queen Mary University of London, 2015-10-03)The number of clinical procedures performed in the USA using bone graft substitutes was estimated at 1.1 million in 2010 and is projected to reach 1.3 million in 2015. This increasing demand for bone graft substitutes ... -
The Role of PKN2 in Colorectal Cancer
Colorectal cancer (CRC) is a globally prevalent malignancy responsible for the second highest number of cancer-related deaths. CRC arises from the accumulation of heritable genomic altercations within the intestinal ... -
The role of platelet-derived growth factor in radiation injury to the lower urinary tract
(Queen Mary University of London, 2011)Approximately half of all patients diagnosed with cancer will receive radiotherapy as a part of the management of their tumours. Radiotherapy allows organ sparing treatment but it is associated with a number of acute and ... -
Role of Plectin in Nuclear Mechano-transduction of Keratinocytes.
(Queen Mary University of London, 12/11/2016)Cell shape dictates nuclear morphology via cytoskeleton remodelling, potentially regulating therefore nuclear architecture and gene expression. Utilising micro-patterned substrates to control cell shape, the physical ... -
Role of Polymeric Immunoglobulin Receptor in pancreatic ductal adenocarcinoma
(Queen Mary University of London, 2017-11-26)Introduction: Polymeric immunoglobulin receptor (pIgR) traffics Immunoglobulins (IgA and IgM) through epithelial cells in normal mucosae but neither are expressed in the normal pancreas. Recent work has demonstrated pIgR ... -
The role of primary cilia and sonic hedgehog signalling in adrenal development function.
(Queen Mary University of London, 2012)Primary cilia are sensory organelles found on most vertebrate cells during interphase. They play key roles in development, cell signalling and cancer, and are involved in signal transduction pathways such as Hh and Wnt ...