dc.contributor.author | Mohammadi, A | |
dc.contributor.author | Farabi, H | |
dc.contributor.author | Baghdadabad, LZ | |
dc.contributor.author | Narouie, B | |
dc.contributor.author | Reis, LO | |
dc.contributor.author | Aghamir, SMK | |
dc.date.accessioned | 2024-05-30T13:41:31Z | |
dc.date.available | 2023-08-14 | |
dc.date.available | 2024-05-30T13:41:31Z | |
dc.date.issued | 2023-08-27 | |
dc.identifier.citation | Mohammadi, A., Farabi, H., Baghdadabad, L.Z. et al. Serum and 24-hour urinary tests cost-effectiveness in stone formers. BMC Urol 23, 141 (2023). https://doi.org/10.1186/s12894-023-01310-w | en_US |
dc.identifier.issn | 1471-2490 | |
dc.identifier.other | ARTN 141 | |
dc.identifier.uri | https://qmro.qmul.ac.uk/xmlui/handle/123456789/97115 | |
dc.description.abstract | Objective
To assess the routine serum and 24-hour urine tests proficiency in diagnosing the baseline metabolic abnormality of kidney stone formers.
Methods
This study analyzes the routine serum and 24-hour urine tests proficiency in diagnosing the baseline metabolic abnormality of kidney stone formers. The sensitivity and specificity, false positive, and negative results of the tests are extracted from diagnostic kits used in the laboratories of the target community. To accurately infer the results, a simulation based on 1000 people was used through 22 standard laboratory tests (Additional File 2), including calcium, oxalate, phosphate, uric acid, sulfate, potassium, sodium, citrate, and magnesium in 24-hour urine; and calcium, creatinine, Vit D, uric acid, and intact parathyroid hormone (PTH) in serum. The incremental cost-effectiveness ratio (ICER) was calculated and compared for each diagnostic test versus other diagnostic tests according to the incremental cost required for correct diagnoses of stone causes.
Results
Urinary uric acid, citrate, and serum potassium constitute the cost-effectiveness boundary curve in this study. This means that other diagnostic tests are not cost-effective compared to these three tests in terms of indexing at least one item of cost and effectiveness. The ICER index for each correct diagnosis with the urinary uric acid test was $ 1.25 per diagnosis, the most cost-effective test compared to serum potassium and urinary citrate.
Conclusion
The simplified blood and 24-hour urine metabolic evaluation, including urinary uric acid, citrate, and serum potassium, constitute the cost-effectiveness boundary curve. The most cost-effective test was urinary uric acid measurement. | en_US |
dc.publisher | BMC | en_US |
dc.relation.ispartof | BMC UROLOGY | |
dc.rights | This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. | |
dc.subject | Urolithiasis | en_US |
dc.subject | Metabolic evaluation | en_US |
dc.subject | Recurrent kidney stone | en_US |
dc.subject | 24-hour urinary test | en_US |
dc.subject | Cost-effectiveness | en_US |
dc.title | Serum and 24-hour urinary tests cost-effectiveness in stone formers | en_US |
dc.type | Article | en_US |
dc.identifier.doi | 10.1186/s12894-023-01310-w | |
pubs.author-url | https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:001054982600001&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=612ae0d773dcbdba3046f6df545e9f6a | en_US |
pubs.issue | 1 | en_US |
pubs.notes | Not known | en_US |
pubs.publication-status | Published | en_US |
pubs.volume | 23 | en_US |
rioxxterms.funder | Default funder | en_US |
rioxxterms.identifier.project | Default project | en_US |
rioxxterms.funder.project | 2acae7f5-fd8c-4d20-af2e-447fb9664166 | en_US |