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dc.contributor.authorBenucci, Aen_US
dc.contributor.authorSaleem, ABen_US
dc.contributor.authorCarandini, Men_US
dc.date.accessioned2024-05-10T13:52:50Z
dc.date.available2013-03-25en_US
dc.date.issued2013-06en_US
dc.identifier.urihttps://qmro.qmul.ac.uk/xmlui/handle/123456789/96784
dc.description.abstractSensory systems exhibit mechanisms of neural adaptation, which adjust neuronal activity on the basis of recent stimulus history. In primary visual cortex (V1) in particular, adaptation controls the responsiveness of individual neurons and shifts their visual selectivity. What benefits does adaptation confer on a neuronal population? We measured adaptation in the responses of populations of cat V1 neurons to stimulus ensembles with markedly different statistics of stimulus orientation. We found that adaptation served two homeostatic goals. First, it maintained equality in the time-averaged responses across the population. Second, it maintained independence in selectivity across the population. Adaptation scaled and distorted population activity according to a simple multiplicative rule that depended on neuronal orientation preference and on stimulus orientation. We conclude that adaptation in V1 acts as a mechanism of homeostasis, enforcing a tendency toward equality and independence in neural activity across the population.en_US
dc.format.extent724 - 729en_US
dc.languageengen_US
dc.relation.ispartofNat Neuroscien_US
dc.subjectAdaptation, Physiologicalen_US
dc.subjectAdaptation, Psychologicalen_US
dc.subjectAnimalsen_US
dc.subjectCatsen_US
dc.subjectElectrodes, Implanteden_US
dc.subjectElectroencephalographyen_US
dc.subjectFemaleen_US
dc.subjectHomeostasisen_US
dc.subjectModels, Neurologicalen_US
dc.subjectNeuronsen_US
dc.subjectNeuropsychological Testsen_US
dc.subjectVisual Cortexen_US
dc.titleAdaptation maintains population homeostasis in primary visual cortex.en_US
dc.typeArticle
dc.identifier.doi10.1038/nn.3382en_US
pubs.author-urlhttps://www.ncbi.nlm.nih.gov/pubmed/23603708en_US
pubs.issue6en_US
pubs.notesNot knownen_US
pubs.publication-statusPublisheden_US
pubs.volume16en_US
dcterms.dateAccepted2013-03-25en_US
rioxxterms.funderDefault funderen_US
rioxxterms.identifier.projectDefault projecten_US


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