Browsing Centre for Cancer Genomics & Computational Biology by Author "Nulsen, J"
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Comparative assessment of genes driving cancer and somatic evolution in non-cancer tissues: an update of the Network of Cancer Genes (NCG) resource.
Dressler, L; Bortolomeazzi, M; Keddar, MR; Misetic, H; Sartini, G; Acha-Sagredo, A; Montorsi, L; Wijewardhane, N; Repana, D; Nulsen, J (2022-01-26)BACKGROUND: Genetic alterations of somatic cells can drive non-malignant clone formation and promote cancer initiation. However, the link between these processes remains unclear and hampers our understanding of tissue ... -
Pan-cancer detection of driver genes at the single-patient resolution.
Nulsen, J; Misetic, H; Yau, C; Ciccarelli, FD (2021-02-01)BACKGROUND: Identifying the complete repertoire of genes that drive cancer in individual patients is crucial for precision oncology. Most established methods identify driver genes that are recurrently altered across patient ...