Browsing Centre for Cancer Genomics & Computational Biology by Author "Misetic, H"
Now showing items 1-4 of 4
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Comparative assessment of genes driving cancer and somatic evolution in non-cancer tissues: an update of the Network of Cancer Genes (NCG) resource.
Dressler, L; Bortolomeazzi, M; Keddar, MR; Misetic, H; Sartini, G; Acha-Sagredo, A; Montorsi, L; Wijewardhane, N; Repana, D; Nulsen, J (2022-01-26)BACKGROUND: Genetic alterations of somatic cells can drive non-malignant clone formation and promote cancer initiation. However, the link between these processes remains unclear and hampers our understanding of tissue ... -
Exome sequencing of hepatocellular carcinoma in lemurs identifies potential cancer drivers: A pilot study
Gunady, EF; Ware, KE; Hoskinson Plumlee, S; Devos, N; Corcoran, D; Prinz, J; Misetic, H; Ciccarelli, FD; Harrison, TM; Thorne, JL (Oxford University Press, 2022-04-29)BACKGROUND AND OBJECTIVES: Hepatocellular carcinoma occurs frequently in prosimians, but the cause of these liver cancers in this group is unknown. Characterizing the genetic changes associated with hepatocellular carcinoma ... -
Mechanistic insights into the interactions between cancer drivers and the tumour immune microenvironment.
Misetic, H; Keddar, MR; Jeannon, J-P; Ciccarelli, FD (2023-06-05)BACKGROUND: The crosstalk between cancer and the tumour immune microenvironment (TIME) has attracted significant interest in the latest years because of its impact on cancer evolution and response to treatment. Despite ... -
Pan-cancer detection of driver genes at the single-patient resolution.
Nulsen, J; Misetic, H; Yau, C; Ciccarelli, FD (2021-02-01)BACKGROUND: Identifying the complete repertoire of genes that drive cancer in individual patients is crucial for precision oncology. Most established methods identify driver genes that are recurrently altered across patient ...